Phosphatidylinositol 3-Kinase-dependent Activation of Protein Kinase C-ζ in Bacterial Lipopolysaccharide-treated Human Monocytes

The isoform identity of activated protein kinase C (PKC) and its regulation were investigated in bacterial lipopolysaccharide (LPS)-treated human monocytes. Resolution of detergent-soluble lysates prepared from LPS-treated, peripheral blood monocytes using Mono Q anion-exchange chromatography reveal...

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Veröffentlicht in:	The Journal of biological chemistry 1997-06, Vol.272 (26), p.16445-16452
Hauptverfasser:	Herrera-Velit, Patricia, Knutson, Keith L., Reiner, Neil E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Cell Line Enzyme Activation - drug effects Humans Isoenzymes - drug effects Isoenzymes - metabolism Lipopolysaccharides - pharmacology Molecular Sequence Data Monocytes - drug effects Monocytes - enzymology Phosphatidylinositol 3-Kinases Phosphotransferases (Alcohol Group Acceptor) - physiology Protein Kinase C - drug effects Protein Kinase C - metabolism
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