Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma

Protein tyrosine kinases (PTKs) have been implicated in the development of many common human tumours including melanoma. Previously we isolated PTK gene sequences expressed in normal melanocytes. Here we examined expression of 9 of these genes in cell lines derived from defined stages of melanoma pr...

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Veröffentlicht in:	International journal of cancer 1997-06, Vol.71 (6), p.1061-1065
Hauptverfasser:	Easty, David J., Mitchell, Philip J., Patel, Ketan, Florenes, Vivi Ann, Spritz, Richard A., Bennett, Dorothy C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Adhesion Molecules Dermatology Fetal Proteins - genetics Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans Medical sciences Melanoma - enzymology Melanoma - genetics Melanoma - pathology Neoplasm Metastasis Receptor Protein-Tyrosine Kinases - genetics Receptor, EphA4 RNA, Messenger - genetics Tumors of the skin and soft tissue. Premalignant lesions
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