Characterization of 10 new monoclonal antibodies against prostate‐specific antigen by analysis of affinity, specificity and function in sandwich assays

While prostate‐specific antigen (PSA) is already an invaluable marker for prostate cancer, there is continuing demand for new anti‐PSA antibodies with specific characteristics, e.g., high sensitivity and specificity and equimolar binding to free PSA (f‐PSA) and the PSA‐α‐1‐antichymotrypsin complex (...

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Veröffentlicht in:	International journal of cancer 1997-06, Vol.71 (6), p.1019-1028
Hauptverfasser:	Corey, Eva, Wegner, Sandra K., Stray, James E., Corey, Michael J., Arfman, Edward W., Lange, Paul H., Vessella, Robert L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibody Affinity Antibody Specificity Antineoplastic agents Biological and medical sciences Blotting, Western Enzyme-Linked Immunosorbent Assay Immunotherapy Medical sciences Mice Mice, Inbred BALB C Pharmacology. Drug treatments Prostate-Specific Antigen - immunology Sensitivity and Specificity
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