Acute Corticosterone Replacement Reinstates Performance on Spatial and Nonspatial Memory Tasks 3 Months After Adrenalectomy Despite Degeneration in the Dentate Gyrus

Long-term adrenalectomy (ADX) causes loss of spatial memory and of dentate gyrus cells. These effects are prevented by chronic replacement of corticosterone (CORT). The effects of acute replacement 3 months after ADX in rats classified as ADX or incomplete ADX (INC) on the basis of saline intake, we...

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Veröffentlicht in:	Behavioral neuroscience 1997-06, Vol.111 (3), p.518-531
Hauptverfasser:	McCormick, Cheryl M, McNamara, Megan, Mukhopadhyay, Shiuli, Kelsey, John E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenalectomy Animal Animals Behavioral psychophysiology Biological and medical sciences Corticosterone Corticosterone - pharmacology Corticosterone - physiology Dentate Gyrus - drug effects Dentate Gyrus - physiology Escape Reaction - drug effects Escape Reaction - physiology Fundamental and applied biological sciences. Psychology Hippocampus Hormones and behavior Male Maze Learning - drug effects Maze Learning - physiology Mental Recall - drug effects Mental Recall - physiology Motor Activity - drug effects Motor Activity - physiology Nerve Degeneration - drug effects Nerve Degeneration - physiology Neural Development Neurology Orientation - drug effects Orientation - physiology Pattern Recognition, Visual - drug effects Pattern Recognition, Visual - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Reaction Time - drug effects Reaction Time - physiology Rodents Spatial Memory Steroids
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