A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome

The human Dubin‐Johnson syndrome (DJS) is a rare autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. Patients have impaired hepatobiliary transport of non‐bile salt organic anions. A highly similar phenotype has been described for a mutant Wistar rat strain, th...

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