The germline repertoire of T-cell receptor beta-chain genes in patients with multiple sclerosis

The T-cell receptor (TCR) beta-chain gene repertoire of 40 multiple sclerosis (MS) patients was compared to that of 100 normal individuals. V-beta probes that represent 14 different V-beta sub-families plus a C-beta probe were used to identify 53 separate beta-chain gene segments. No duplication or...

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Veröffentlicht in:Research in immunology (Paris) 1989-01, Vol.140 (2), p.212-215
Hauptverfasser: Biddison, W.E., Beall, S.S., Concannon, P., Charmley, P., Gatti, R.A., Hood, L.E., McFarland, H.F., McFarlin, D.E.
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Sprache:eng
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