Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists
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Veröffentlicht in: | Journal of medicinal chemistry 1997-06, Vol.40 (12), p.1771-1772 |
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container_end_page | 1772 |
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container_issue | 12 |
container_start_page | 1771 |
container_title | Journal of medicinal chemistry |
container_volume | 40 |
creator | Glase, Shelly A Akunne, Hyacinth C Georgic, Lynn M Heffner, Thomas G MacKenzie, Robert G Manley, Peter J Pugsley, Thomas A Wise, Lawrence D |
description | |
doi_str_mv | 10.1021/jm970021c |
format | Article |
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Neurotransmission. Receptors ; Pharmacology. Drug treatments ; Piperazines - chemical synthesis ; Piperazines - metabolism ; Piperazines - pharmacology ; Receptors, Dopamine D2 - agonists ; Receptors, Dopamine D2 - genetics ; Receptors, Dopamine D2 - metabolism ; Receptors, Dopamine D4 ; Structure-Activity Relationship ; Transfection</subject><ispartof>Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1771-1772</ispartof><rights>Copyright © 1997 American Chemical Society</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jm970021c$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jm970021c$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2688634$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9191952$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Glase, Shelly A</creatorcontrib><creatorcontrib>Akunne, Hyacinth C</creatorcontrib><creatorcontrib>Georgic, Lynn M</creatorcontrib><creatorcontrib>Heffner, Thomas G</creatorcontrib><creatorcontrib>MacKenzie, Robert G</creatorcontrib><creatorcontrib>Manley, Peter J</creatorcontrib><creatorcontrib>Pugsley, Thomas A</creatorcontrib><creatorcontrib>Wise, Lawrence D</creatorcontrib><title>Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists</title><title>Journal of medicinal chemistry</title><addtitle>J. Med. Chem</addtitle><subject>Animals</subject><subject>Benzamides - chemical synthesis</subject><subject>Benzamides - metabolism</subject><subject>Benzamides - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Catecholaminergic system</subject><subject>CHO Cells</subject><subject>Cricetinae</subject><subject>Dopamine Antagonists - pharmacology</subject><subject>Haloperidol - pharmacology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Molecular Structure</subject><subject>Neuropharmacology</subject><subject>Neurotransmitters. Neurotransmission. Receptors</subject><subject>Pharmacology. Drug treatments</subject><subject>Piperazines - chemical synthesis</subject><subject>Piperazines - metabolism</subject><subject>Piperazines - pharmacology</subject><subject>Receptors, Dopamine D2 - agonists</subject><subject>Receptors, Dopamine D2 - genetics</subject><subject>Receptors, Dopamine D2 - metabolism</subject><subject>Receptors, Dopamine D4</subject><subject>Structure-Activity Relationship</subject><subject>Transfection</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kc1q3DAUhUVJmEwnXeQBAl4kpVk4lWRLsrIb8ls6JIGZlkAJQpavE038F8sOnVl129fsk0RlzHAXOpzzXcG9F6EDgk8JpuTrspQCe2E-oDFhFIdxguMdNPYeDSmn0R766NwSYxwRGo3QSBJfjI7Rw7xPXWe7voMs-PUlDu-foVoVjW2g1Wvr5UkYlNA9r4rHFKq1Lm0G7uzfn7_BHAownX2D4KJuvF95EQfTp7qyrnP7aDfXhYNPwztBP64uF-c34ezu-tv5dBZqSjgNpUi51nkucJKDkDSTWAtGGfVWJkTCWJ4QnZAoBS5lzHLJM2NMHnmYMD_MBH3e_Nu09WsPrlOldQaKQldQ904JiX0jZx48HMA-LSFTTWtL3a7UsAqfHw25dkYXeasrY90WozxJeBR7LNxgfkj4vY11-6K4iARTi_u5WsTy5y2-_q6k5483vDZOLeu-rfw2FMHq_-HU9nDRO9_8h30</recordid><startdate>19970606</startdate><enddate>19970606</enddate><creator>Glase, Shelly A</creator><creator>Akunne, Hyacinth C</creator><creator>Georgic, Lynn M</creator><creator>Heffner, Thomas G</creator><creator>MacKenzie, Robert G</creator><creator>Manley, Peter J</creator><creator>Pugsley, Thomas A</creator><creator>Wise, Lawrence D</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19970606</creationdate><title>Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists</title><author>Glase, Shelly A ; Akunne, Hyacinth C ; Georgic, Lynn M ; Heffner, Thomas G ; MacKenzie, Robert G ; Manley, Peter J ; Pugsley, Thomas A ; Wise, Lawrence D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a2162-97b6aaff708fe792d90a75252ff7d77855f81a813be69945f96dcccf3e7915123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Animals</topic><topic>Benzamides - chemical synthesis</topic><topic>Benzamides - metabolism</topic><topic>Benzamides - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Catecholaminergic system</topic><topic>CHO Cells</topic><topic>Cricetinae</topic><topic>Dopamine Antagonists - pharmacology</topic><topic>Haloperidol - pharmacology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Molecular Structure</topic><topic>Neuropharmacology</topic><topic>Neurotransmitters. Neurotransmission. Receptors</topic><topic>Pharmacology. Drug treatments</topic><topic>Piperazines - chemical synthesis</topic><topic>Piperazines - metabolism</topic><topic>Piperazines - pharmacology</topic><topic>Receptors, Dopamine D2 - agonists</topic><topic>Receptors, Dopamine D2 - genetics</topic><topic>Receptors, Dopamine D2 - metabolism</topic><topic>Receptors, Dopamine D4</topic><topic>Structure-Activity Relationship</topic><topic>Transfection</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Glase, Shelly A</creatorcontrib><creatorcontrib>Akunne, Hyacinth C</creatorcontrib><creatorcontrib>Georgic, Lynn M</creatorcontrib><creatorcontrib>Heffner, Thomas G</creatorcontrib><creatorcontrib>MacKenzie, Robert G</creatorcontrib><creatorcontrib>Manley, Peter J</creatorcontrib><creatorcontrib>Pugsley, Thomas A</creatorcontrib><creatorcontrib>Wise, Lawrence D</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Glase, Shelly A</au><au>Akunne, Hyacinth C</au><au>Georgic, Lynn M</au><au>Heffner, Thomas G</au><au>MacKenzie, Robert G</au><au>Manley, Peter J</au><au>Pugsley, Thomas A</au><au>Wise, Lawrence D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists</atitle><jtitle>Journal of medicinal chemistry</jtitle><addtitle>J. Med. Chem</addtitle><date>1997-06-06</date><risdate>1997</risdate><volume>40</volume><issue>12</issue><spage>1771</spage><epage>1772</epage><pages>1771-1772</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><coden>JMCMAR</coden><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>9191952</pmid><doi>10.1021/jm970021c</doi><tpages>2</tpages></addata></record> |
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ispartof | Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1771-1772 |
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language | eng |
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source | MEDLINE; American Chemical Society Journals |
subjects | Animals Benzamides - chemical synthesis Benzamides - metabolism Benzamides - pharmacology Biological and medical sciences Catecholaminergic system CHO Cells Cricetinae Dopamine Antagonists - pharmacology Haloperidol - pharmacology Humans Medical sciences Molecular Structure Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Piperazines - chemical synthesis Piperazines - metabolism Piperazines - pharmacology Receptors, Dopamine D2 - agonists Receptors, Dopamine D2 - genetics Receptors, Dopamine D2 - metabolism Receptors, Dopamine D4 Structure-Activity Relationship Transfection |
title | Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D4 Agonists |
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