TrnR2, a Novel Receptor That Mediates Neurturin and GDNF Signaling through Ret

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) comprise a family of TGF-β-related neurotrophic factors (TRNs), which have trophic influences on a variety of neuronal populations. A receptor complex comprised of TrnR1 (GDNFRα) and Ret was recently identified and found to be ca...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1997-05, Vol.18 (5), p.793-802
Hauptverfasser:	Baloh, Robert H., Tansey, Malú G., Golden, Judith P., Creedon, Douglas J., Heuckeroth, Robert O., Keck, Catherine L., Zimonjic, Drazen B., Popescu, Nicholas C., Johnson, Eugene M., Milbrandt, Jeffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells - chemistry 3T3 Cells - metabolism Age Factors Animals Animals, Newborn Base Sequence Blotting, Northern Brain Chemistry - physiology Chromosome Mapping Drosophila Proteins Gene Expression - physiology Glial Cell Line-Derived Neurotrophic Factor Glial Cell Line-Derived Neurotrophic Factor Receptors In Situ Hybridization, Fluorescence Male Mice Molecular Sequence Data Nerve Growth Factors - pharmacology Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - pharmacology Neurons - chemistry Neurons - cytology Neurons - drug effects Neurturin Proto-Oncogene Proteins - physiology Proto-Oncogene Proteins c-ret Rats Receptor Protein-Tyrosine Kinases - physiology RNA, Messenger - analysis Sciatic Nerve - chemistry Sciatic Nerve - cytology Sciatic Nerve - injuries Sequence Homology, Amino Acid Signal Transduction - drug effects Signal Transduction - physiology Testis - chemistry Up-Regulation - physiology
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