MRI of the brain and craniocervical junction in Morquio's disease
We reviewed MRI of the brain and cervical spine in 11 patients with Morquio's disease. No abnormality was seen in the brain. The odontoid peg was abnormal in all patients, with varying degrees of cord compression due to an anterior soft tissue mass and indentation by the posterior arch of the a...
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| Veröffentlicht in: | Neuroradiology 1997-05, Vol.39 (5), p.381-385 |
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| container_title | Neuroradiology |
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| creator | HUGHES, D. G CHADDERTON, R. D COWIE, R. A WRAITH, J. E JENKINS, J. P. R |
| description | We reviewed MRI of the brain and cervical spine in 11 patients with Morquio's disease. No abnormality was seen in the brain. The odontoid peg was abnormal in all patients, with varying degrees of cord compression due to an anterior soft tissue mass and indentation by the posterior arch of the atlas. The degree of cord compression was more marked than suggested by the symptoms and signs. We recommend MRI of the cervical spine in children with Morquio's disease before the development of neurological symptoms, to optimise the timing and type of surgical intervention. |
| doi_str_mv | 10.1007/s002340050429 |
| format | Article |
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We recommend MRI of the cervical spine in children with Morquio's disease before the development of neurological symptoms, to optimise the timing and type of surgical intervention.</description><identifier>ISSN: 0028-3940</identifier><identifier>EISSN: 1432-1920</identifier><identifier>DOI: 10.1007/s002340050429</identifier><identifier>PMID: 9189888</identifier><identifier>CODEN: NRDYAB</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adolescent ; Biological and medical sciences ; Brain - pathology ; Cervical Vertebrae - pathology ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Investigative techniques, diagnostic techniques (general aspects) ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Mucopolysaccharidosis IV - complications ; Mucopolysaccharidosis IV - diagnosis ; Osteoarticular system. Muscles ; Radiodiagnosis. Nmr imagery. 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D</creatorcontrib><creatorcontrib>COWIE, R. A</creatorcontrib><creatorcontrib>WRAITH, J. E</creatorcontrib><creatorcontrib>JENKINS, J. P. R</creatorcontrib><title>MRI of the brain and craniocervical junction in Morquio's disease</title><title>Neuroradiology</title><addtitle>Neuroradiology</addtitle><description>We reviewed MRI of the brain and cervical spine in 11 patients with Morquio's disease. No abnormality was seen in the brain. The odontoid peg was abnormal in all patients, with varying degrees of cord compression due to an anterior soft tissue mass and indentation by the posterior arch of the atlas. The degree of cord compression was more marked than suggested by the symptoms and signs. We recommend MRI of the cervical spine in children with Morquio's disease before the development of neurological symptoms, to optimise the timing and type of surgical intervention.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Cervical Vertebrae - pathology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mucopolysaccharidosis IV - complications</subject><subject>Mucopolysaccharidosis IV - diagnosis</subject><subject>Osteoarticular system. Muscles</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Spinal Cord - pathology</subject><subject>Spinal Cord Compression - diagnosis</subject><subject>Spinal Cord Compression - etiology</subject><issn>0028-3940</issn><issn>1432-1920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM9LwzAUgIMoc06PHoUcRE_VlyZtk6MMfww2BNFzya9iRtdsSSv435uxMvD04H0fj8eH0DWBBwJQPUaAnDKAAlguTtCUMJpnRORwiqYJ8YwKBufoIsY1ANCKVhM0EYQLzvkUPa0-Ftg3uP-2WAXpOiw7g3WQnfPahh-nZYvXQ6d75zuc8MqH3eD8fcTGRSujvURnjWyjvRrnDH29PH_O37Ll--ti_rTMNCVVn-VccUM40UxoKqucFpwoLZkRspGSpecVURRUYaSm1PCES2MqokoQ-yWdobvD3W3wu8HGvt64qG3bys76IdaVgEIwQZKYHUQdfIzBNvU2uI0MvzWBep-s_pcs-Tfj4UFtrDnaY6PEb0cuY6rRpDbaxaOWlyUnBOgfS0Jx1g</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>HUGHES, D. G</creator><creator>CHADDERTON, R. D</creator><creator>COWIE, R. A</creator><creator>WRAITH, J. E</creator><creator>JENKINS, J. P. 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Nmr spectrometry</topic><topic>Spinal Cord - pathology</topic><topic>Spinal Cord Compression - diagnosis</topic><topic>Spinal Cord Compression - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HUGHES, D. G</creatorcontrib><creatorcontrib>CHADDERTON, R. D</creatorcontrib><creatorcontrib>COWIE, R. A</creatorcontrib><creatorcontrib>WRAITH, J. E</creatorcontrib><creatorcontrib>JENKINS, J. P. R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HUGHES, D. G</au><au>CHADDERTON, R. D</au><au>COWIE, R. A</au><au>WRAITH, J. E</au><au>JENKINS, J. P. R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MRI of the brain and craniocervical junction in Morquio's disease</atitle><jtitle>Neuroradiology</jtitle><addtitle>Neuroradiology</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>39</volume><issue>5</issue><spage>381</spage><epage>385</epage><pages>381-385</pages><issn>0028-3940</issn><eissn>1432-1920</eissn><coden>NRDYAB</coden><abstract>We reviewed MRI of the brain and cervical spine in 11 patients with Morquio's disease. No abnormality was seen in the brain. The odontoid peg was abnormal in all patients, with varying degrees of cord compression due to an anterior soft tissue mass and indentation by the posterior arch of the atlas. The degree of cord compression was more marked than suggested by the symptoms and signs. We recommend MRI of the cervical spine in children with Morquio's disease before the development of neurological symptoms, to optimise the timing and type of surgical intervention.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>9189888</pmid><doi>10.1007/s002340050429</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Biological and medical sciences Brain - pathology Cervical Vertebrae - pathology Child Child, Preschool Female Humans Infant Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging Male Medical sciences Mucopolysaccharidosis IV - complications Mucopolysaccharidosis IV - diagnosis Osteoarticular system. Muscles Radiodiagnosis. Nmr imagery. Nmr spectrometry Spinal Cord - pathology Spinal Cord Compression - diagnosis Spinal Cord Compression - etiology |
| title | MRI of the brain and craniocervical junction in Morquio's disease |
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