ROLE OF CHOLECYSTOKININ IN REGULATION OF GASTROINTESTINAL MOTOR FUNCTIONS

By means of loxiglumide, a potent and highly specific antagonist for cholecystokinin (CCK), the effects of blocking CCK receptors on gastrointestinal motility were investigated in a placebo-controlled study in healthy young men (aged 21-39, mean 24 years). Gallbladder contraction stimulated by inges...

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Veröffentlicht in:	The Lancet (British edition) 1989-07, Vol.334 (8653), p.12-15
Hauptverfasser:	Meyer, BeatM, Beglinger, Christoph, Jansen, JanB.M.J., Rovati, LucioC, Werth, BaseliA, Hildebrand, Pius, Zach, David, Stalder, GeorgA
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Aminobenzoic Acid Administration, Oral Adult Biological and medical sciences Cholecystokinin - antagonists & inhibitors Cholecystokinin - blood Cholecystokinin - physiology Clinical Trials as Topic Colon - physiology Digestive system Drug Evaluation Eating Fundamental and applied biological sciences. Psychology Gallbladder - physiology Gastric Emptying - drug effects Gastrointestinal hormones Gastrointestinal Transit - drug effects Homeostasis - drug effects Humans Infusions, Intravenous Ingestion Intestine, Small - physiology Male Medical disorders Medical research para-Aminobenzoates Proglumide - administration & dosage Proglumide - analogs & derivatives Proglumide - pharmacology Random Allocation Receptors, Cholecystokinin - drug effects Vertebrates: digestive system
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