Primary anastomosis for necrotising enterocolitis: A 12-year experience

Between January 1975 and October 1987, 50 cases of necrotising enterocolitis (NEC) have required surgery. The principle that the best management is resection and exteriorisation of the ends, which was developed in the early 1970s, has been superseded by the realisation that resection and primary ana...

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Veröffentlicht in:Journal of pediatric surgery 1989, Vol.24 (6), p.515-518
Hauptverfasser: Griffiths, D.M., Forbes, D.A., Pemberton, P.J., Penn, I.A.
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container_end_page 518
container_issue 6
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container_title Journal of pediatric surgery
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creator Griffiths, D.M.
Forbes, D.A.
Pemberton, P.J.
Penn, I.A.
description Between January 1975 and October 1987, 50 cases of necrotising enterocolitis (NEC) have required surgery. The principle that the best management is resection and exteriorisation of the ends, which was developed in the early 1970s, has been superseded by the realisation that resection and primary anastomosis can be safe in a well-resuscitated infant in whom the bowel ends appear viable. Eight babies had widespread NEC and no procedure was performed. Thirteen babies had resection and exteriorisation with five long-term survivors (39%). Twenty-nine babies had a primary anastomosis irrespective of birth weight, gestational age, length of resection, or the presence of peritonitis—with 22 (76%) long-term survivors. The pre-operative risk factors and length of bowel resected were similar in the two groups. The length of hospital stay, the period of total parenteral nutrition, the time to full feeds, and the time on a ventilator were all shorter in the primary anastomosis group, with no increase in short-or long-term morbidity or mortality. Provided that the bowel ends are viable, primary anastomosis is the procedure of choice for babies with NEC requiring laparotomy.
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The principle that the best management is resection and exteriorisation of the ends, which was developed in the early 1970s, has been superseded by the realisation that resection and primary anastomosis can be safe in a well-resuscitated infant in whom the bowel ends appear viable. Eight babies had widespread NEC and no procedure was performed. Thirteen babies had resection and exteriorisation with five long-term survivors (39%). Twenty-nine babies had a primary anastomosis irrespective of birth weight, gestational age, length of resection, or the presence of peritonitis—with 22 (76%) long-term survivors. The pre-operative risk factors and length of bowel resected were similar in the two groups. The length of hospital stay, the period of total parenteral nutrition, the time to full feeds, and the time on a ventilator were all shorter in the primary anastomosis group, with no increase in short-or long-term morbidity or mortality. 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The principle that the best management is resection and exteriorisation of the ends, which was developed in the early 1970s, has been superseded by the realisation that resection and primary anastomosis can be safe in a well-resuscitated infant in whom the bowel ends appear viable. Eight babies had widespread NEC and no procedure was performed. Thirteen babies had resection and exteriorisation with five long-term survivors (39%). Twenty-nine babies had a primary anastomosis irrespective of birth weight, gestational age, length of resection, or the presence of peritonitis—with 22 (76%) long-term survivors. The pre-operative risk factors and length of bowel resected were similar in the two groups. The length of hospital stay, the period of total parenteral nutrition, the time to full feeds, and the time on a ventilator were all shorter in the primary anastomosis group, with no increase in short-or long-term morbidity or mortality. Provided that the bowel ends are viable, primary anastomosis is the procedure of choice for babies with NEC requiring laparotomy.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>2738815</pmid><doi>10.1016/S0022-3468(89)80495-6</doi><tpages>4</tpages></addata></record>
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subjects Anastomosis, Surgical - mortality
Anti-Bacterial Agents - therapeutic use
Colostomy - adverse effects
Colostomy - mortality
Enterocolitis, Pseudomembranous - drug therapy
Enterocolitis, Pseudomembranous - surgery
Humans
Ileostomy - adverse effects
Ileostomy - mortality
Infant
Infant, Newborn
Infant, Premature
Intestines - surgery
Necrotising enterocolitis
Postoperative Complications
Retrospective Studies
title Primary anastomosis for necrotising enterocolitis: A 12-year experience
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