The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin
Buccal epithelial cells (BEC) from 12 patients with diabetes mellitus and 12 age‐and sex‐matched non‐diabetic subjects were tested in vitro for adhesion of Candida albicans following exposure to nystatin both in vitro and in vivo. Adhesion was significantly reduced (P < ss0.002) to cells from bot...
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| Veröffentlicht in: | Journal of oral pathology & medicine 1997-05, Vol.26 (5), p.233-236 |
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| container_title | Journal of oral pathology & medicine |
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| creator | Darwazeh, A. M. G. MacFarlane, T. W. Lamey, P.-J. |
| description | Buccal epithelial cells (BEC) from 12 patients with diabetes mellitus and 12 age‐and sex‐matched non‐diabetic subjects were tested in vitro for adhesion of Candida albicans following exposure to nystatin both in vitro and in vivo. Adhesion was significantly reduced (P < ss0.002) to cells from both the diabetic and non‐diabetic subjects after in vitro exposure to nystatin. but the reduction in adhesion was variable (5.0–50.7%) in control subjects and 0.5‐4–8.4% in diabetic subjects) and equivalent between the two groups. In vivo exposure to nystatin produced no overall significant reduction in Candida! adhesion to cells from either diabetic or control subjects. |
| doi_str_mv | 10.1111/j.1600-0714.1997.tb01229.x |
| format | Article |
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In vivo exposure to nystatin produced no overall significant reduction in Candida! adhesion to cells from either diabetic or control subjects.</description><identifier>ISSN: 0904-2512</identifier><identifier>EISSN: 1600-0714</identifier><identifier>DOI: 10.1111/j.1600-0714.1997.tb01229.x</identifier><identifier>PMID: 9178175</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>adhesion ; Adult ; Antifungal Agents - pharmacology ; Antifungal Agents - therapeutic use ; Biological and medical sciences ; Candida albicans ; Candida albicans - drug effects ; Candida albicans - physiology ; Candidiasis, Oral - complications ; Candidiasis, Oral - drug therapy ; Case-Control Studies ; Cell Adhesion - drug effects ; Cell Adhesion - physiology ; Dentistry ; Diabetes Complications ; diabetes mellitus ; Diabetes Mellitus - microbiology ; Diabetes Mellitus - physiopathology ; Ent. 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M. G.</creatorcontrib><creatorcontrib>MacFarlane, T. W.</creatorcontrib><creatorcontrib>Lamey, P.-J.</creatorcontrib><title>The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin</title><title>Journal of oral pathology & medicine</title><addtitle>J Oral Pathol Med</addtitle><description>Buccal epithelial cells (BEC) from 12 patients with diabetes mellitus and 12 age‐and sex‐matched non‐diabetic subjects were tested in vitro for adhesion of Candida albicans following exposure to nystatin both in vitro and in vivo. Adhesion was significantly reduced (P < ss0.002) to cells from both the diabetic and non‐diabetic subjects after in vitro exposure to nystatin. but the reduction in adhesion was variable (5.0–50.7%) in control subjects and 0.5‐4–8.4% in diabetic subjects) and equivalent between the two groups. In vivo exposure to nystatin produced no overall significant reduction in Candida! adhesion to cells from either diabetic or control subjects.</description><subject>adhesion</subject><subject>Adult</subject><subject>Antifungal Agents - pharmacology</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Candida albicans</subject><subject>Candida albicans - drug effects</subject><subject>Candida albicans - physiology</subject><subject>Candidiasis, Oral - complications</subject><subject>Candidiasis, Oral - drug therapy</subject><subject>Case-Control Studies</subject><subject>Cell Adhesion - drug effects</subject><subject>Cell Adhesion - physiology</subject><subject>Dentistry</subject><subject>Diabetes Complications</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus - microbiology</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Ent. Stomatology</subject><subject>Epithelial Cells</subject><subject>Epithelium - microbiology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mouth Mucosa - microbiology</subject><subject>nystatin</subject><subject>Nystatin - pharmacology</subject><subject>Nystatin - therapeutic use</subject><subject>Pharmacology. 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W.</creator><creator>Lamey, P.-J.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199705</creationdate><title>The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin</title><author>Darwazeh, A. M. G. ; MacFarlane, T. W. ; Lamey, P.-J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4363-d0fbcb15d08aca168e08714b640fe73a0c5e5b586f9414305e438a8b5c12ba2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>adhesion</topic><topic>Adult</topic><topic>Antifungal Agents - pharmacology</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Candida albicans</topic><topic>Candida albicans - drug effects</topic><topic>Candida albicans - physiology</topic><topic>Candidiasis, Oral - complications</topic><topic>Candidiasis, Oral - drug therapy</topic><topic>Case-Control Studies</topic><topic>Cell Adhesion - drug effects</topic><topic>Cell Adhesion - physiology</topic><topic>Dentistry</topic><topic>Diabetes Complications</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus - microbiology</topic><topic>Diabetes Mellitus - physiopathology</topic><topic>Ent. Stomatology</topic><topic>Epithelial Cells</topic><topic>Epithelium - microbiology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mouth Mucosa - microbiology</topic><topic>nystatin</topic><topic>Nystatin - pharmacology</topic><topic>Nystatin - therapeutic use</topic><topic>Pharmacology. Drug treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Darwazeh, A. M. G.</creatorcontrib><creatorcontrib>MacFarlane, T. 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W.</au><au>Lamey, P.-J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin</atitle><jtitle>Journal of oral pathology & medicine</jtitle><addtitle>J Oral Pathol Med</addtitle><date>1997-05</date><risdate>1997</risdate><volume>26</volume><issue>5</issue><spage>233</spage><epage>236</epage><pages>233-236</pages><issn>0904-2512</issn><eissn>1600-0714</eissn><abstract>Buccal epithelial cells (BEC) from 12 patients with diabetes mellitus and 12 age‐and sex‐matched non‐diabetic subjects were tested in vitro for adhesion of Candida albicans following exposure to nystatin both in vitro and in vivo. Adhesion was significantly reduced (P < ss0.002) to cells from both the diabetic and non‐diabetic subjects after in vitro exposure to nystatin. but the reduction in adhesion was variable (5.0–50.7%) in control subjects and 0.5‐4–8.4% in diabetic subjects) and equivalent between the two groups. In vivo exposure to nystatin produced no overall significant reduction in Candida! adhesion to cells from either diabetic or control subjects.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>9178175</pmid><doi>10.1111/j.1600-0714.1997.tb01229.x</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | adhesion Adult Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Biological and medical sciences Candida albicans Candida albicans - drug effects Candida albicans - physiology Candidiasis, Oral - complications Candidiasis, Oral - drug therapy Case-Control Studies Cell Adhesion - drug effects Cell Adhesion - physiology Dentistry Diabetes Complications diabetes mellitus Diabetes Mellitus - microbiology Diabetes Mellitus - physiopathology Ent. Stomatology Epithelial Cells Epithelium - microbiology Female Humans Male Medical sciences Mouth Mucosa - microbiology nystatin Nystatin - pharmacology Nystatin - therapeutic use Pharmacology. Drug treatments |
| title | The in vitro adhesion of Candida albicans to buccal epithelial cells (BEC) from diabetic and non-diabetic individuals after in vivo and in vitro application of nystatin |
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