Detection of anionic sites and immunoglobulin a deposits in the glomerular capillary walls from patients with Iga nephropathy

A study of anionic sites in the glomerular basement membrane (GBM) from patients with immunoglobulin A (IgA) nephropathy is described. The relationship between the deposition of IgA and the detection of glomerular extracellular components, i.e., noncollagenous (NC‐1) domain of Type IV collagen, in t...

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Veröffentlicht in:	Journal of clinical laboratory analysis 1989, Vol.3 (2), p.101-107
Hauptverfasser:	Tomino, Yasuhiko, Yagame, Mitsunori, Eguchi, Kazuhiko, Miyazaki, Masanobu, Nomoto, Yasuo, Sakai, Hideto, Shirato, Isao, Ito, Kiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	anionic sites Basement Membrane - immunology Basement Membrane - pathology Capillaries - pathology Collagen - analysis Female Fluorescent Antibody Technique Glomerular Mesangium - blood supply Glomerular Mesangium - immunology Glomerular Mesangium - pathology Glomerulonephritis, IGA - immunology Glomerulonephritis, IGA - pathology Glomerulonephritis, IGA - physiopathology Humans IgA deposits IgA nephropathy Immunoglobulin A - analysis Male NC-1 domain of Type IV collagen polyethyleneimine Polyethyleneimine - metabolism Polyethylenes - metabolism Proteinuria - etiology
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