Persistence of Abnormal Chloride Conductance Regulation in Transformed Cystic Fibrosis Epithelia

An airway epithelial cell line (CF/T43) was developed by infecting cultured airway epithelial cells from patients with cystic fibrosis (CF) with the pZIPneoSV(X)1/SV40T retrovirus and selecting for G418 resistance and ion transport properties. The distinctive chloride secretory phenotypes of the CF...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1989-06, Vol.244 (4911), p.1472-1475
Hauptverfasser:	Jetten, Anton M., Yankaskas, James R., Stutts, M. Jackson, Willumsen, Niels J., Boucher, Richard C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amiloride - pharmacology Analysis Antigens, Polyomavirus Transforming - genetics Biochemistry Biological and medical sciences Calcimycin - pharmacology Cell Line Cell lines Cell Membrane - physiology Cell membranes Cell physiology Chloride Channels Chlorides - physiology Colforsin - pharmacology Conductometric analysis Cultured cells Cystic fibrosis Cystic Fibrosis - pathology Cystic Fibrosis - physiopathology Electric Conductivity Electric potential Epithelial cells epithelium Epithelium - drug effects Epithelium - pathology Epithelium - physiology Ethers - pharmacology Freeze Fracturing Fundamental and applied biological sciences. Psychology Genetic vectors Humans Intercellular Junctions Ion Channels - physiology Ionomycin man Membrane and intracellular transports Membrane Proteins - physiology Microscopy, Electron Molecular and cellular biology Nasal Polyps NIH 3T3 cells Phenotypes Property lines Simian virus 40 - immunology Tight junctions Transformation, Genetic transformed cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!