WR 238605, Chloroquine, and their Combinations as Blood Schizonticides against a Chloroquine-Resistant Strain of Plasmodium vivax in Aotus Monkeys

The compound WR 238605 is a primaquine analog being developed by the U.S. Army as an antimalarial drug. Currently, there is no established treatment for Plasmodium vivax parasitemias that are not cured by chloroquine. This study tested WR 238605, chloroquine, and their combinations against a chloroq...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 1997-05, Vol.56 (5), p.508-510
Hauptverfasser:	Obaldia, Nicanor, III, Rossan, Richard N, Cooper, Robert D, Kyle, Dennis E, Nuzum, Edwin O, Rieckmann, Karl H, Shanks, G. Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoquinolines - administration & dosage Aminoquinolines - therapeutic use Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - therapeutic use Antiparasitic agents Aotus trivirgatus Biological and medical sciences Chloroquine - administration & dosage Chloroquine - therapeutic use Drug Resistance Drug Therapy, Combination Human protozoal diseases Infectious diseases Malaria Malaria, Vivax - drug therapy Medical sciences Parasitemia - drug therapy Parasitic diseases Pharmacology. Drug treatments Plasmodium vivax Protozoal diseases Tropical medicine
Online-Zugang:	Volltext
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