Activity of centrally truncated analogues of neuropeptide Y at Y1 and Y2 receptor subtypes in vivo

Neuropeptide Y (NPY), a sympathetic cotransmitter, has both prejunctional and postjunctional actions in the cardiovascular system. In anaesthetized rats, the bioassay system used here, NPY attenuates cardiac vagal action (a prejunctional or Y2 action) and increases blood pressure (a postjunctional o...

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Veröffentlicht in:	Neuropeptides (Edinburgh) 1997-04, Vol.31 (2), p.193-197
Hauptverfasser:	MCCLOSKEY, M. J. D, MORIARTY, M. J, TSENG, A, SHINE, J, POTTER, E. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Blood Pressure - drug effects Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Fundamental and applied biological sciences. Psychology Heart - innervation Molecular Sequence Data Neuropeptide Y - analogs & derivatives Neuropeptide Y - chemical synthesis Neuropeptide Y - chemistry Neuropeptide Y - pharmacology Protein Conformation Rats Rats, Inbred WKY Receptors, Neuropeptide Y - drug effects Receptors, Neuropeptide Y - physiology Structure-Activity Relationship Time Factors Vagus Nerve - drug effects Vagus Nerve - physiology Vertebrates: nervous system and sense organs
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