Renin Inhibitor and Converting Enzyme Inhibitors Suppress Vascular Angiotensin II

The direct effects of a renin inhibitor, N-acetyl-pepstatin and five angiotensin converting enzyme inhibitors, captopril and the active diacid forms of enalapril, ramipril, cilazapril, and CS-622, on the vascular renin-angiotensin system were examined in isolated perfused rat mesenteric arteries. Va...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1989-06, Vol.13 (6, Part 2), p.749-753
Hauptverfasser:	Saito, Hiroshi, Nakamaru, Mitsuaki, Ogihara, Toshio, Rakugi, Hiromi, Kumahara, Yuichi, Shimamoto, Kazuaki, Miyazaki, Mizuo, Inagami, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - antagonists & inhibitors Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Dose-Response Relationship, Drug In Vitro Techniques Male Mesenteric Arteries - metabolism Oligopeptides - pharmacology Pepstatins - pharmacology Perfusion Rats Rats, Inbred Strains Renin - antagonists & inhibitors Renin-Angiotensin System - drug effects
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