Polycystin: In vitro Synthesis, in vivo Tissue Expression, and Subcellular Localization Identifies a Large Membrane-Associated Protein

The primary structure of polycystin predicts a large integral membrane protein with multiple cell recognition motifs, but its function remains unknown. Insight into polycystin's normal function and its role in the development of autosomal dominant polycystic kidney disease (PKD1) requires the a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1997-06, Vol.94 (12), p.6397-6402
Hauptverfasser:	Ibraghimov-Beskrovnaya, Oxana, Dackowski, William R., Foggensteiner, Lukas, Coleman, Nick, Thiru, Sathia, Petry, Linda R., Burn, Timothy C., Connors, Timothy D., Van Raay, Terence, Bradley, John, Qian, Feng, Onuchic, Luiz F., Watnick, Terry J., Piontek, Klaus, Hakim, Raymond M., Landes, Gregory M., Germino, Gregory G., Sandford, Richard, Klinger, Katherine W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Biological Sciences Brain - embryology Brain - metabolism Cell Line Cells, Cultured Cellular biology Complementary DNA Cysts Deoxyribonucleic acid DNA DNA, Complementary Endothelial cells Endothelium, Vascular - metabolism Epithelial cells Epithelium - metabolism Fetus Gene Library Human umbilical vein endothelial cells Humans Kidney - metabolism Kidneys Laboratory staining techniques Medical research Nephrons - embryology Nephrons - metabolism Organ Specificity Polycystic Kidney, Autosomal Dominant Polymerase Chain Reaction Protein Biosynthesis Proteins Proteins - chemistry Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry Subcellular Fractions - metabolism TRPP Cation Channels
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!