Concomitant down-regulation of expression of integrin subunits by N-myc in human neuroblastoma cells: differential regulation of alpha2, alpha3 and beta1

Amplification and over-expression of the N-myc oncogene is associated with the progression of neuroblastoma in children and in a nude mouse model system. Neuroblastoma cell lines with widely different levels of N-myc illustrate an inverse relationship between N-myc over-expression and reduced expres...

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Veröffentlicht in:	Oncogene 1997-03, Vol.14 (11), p.1341-1350
Hauptverfasser:	Judware, R, Culp, L A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - genetics Down-Regulation Genes, myc Humans Integrin alpha2 Integrin alpha3 Integrin beta1 - genetics Integrins - genetics Neuroblastoma - genetics RNA, Messenger - genetics Tumor Cells, Cultured
Online-Zugang:	Volltext
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