Parathyroid hormone increases bone formation and improves mineral balance in vitamin D-deficient female rats

The present study was designed to investigate whether enhanced bone formation due to intermittent PTH administration is dependent on vitamin D metabolites. Forty-eight female Sprague-Dawley rats were randomized into four groups: 1) vitamin D-sufficient, saline-injected (+D Sal); 2) vitamin D-suffici...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1997-06, Vol.138 (6), p.2449-2457
Hauptverfasser:	Toromanoff, A, Ammann, P, Mosekilde, L, Thomsen, J S, Riond, J L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - blood Animals Biomechanical Phenomena Bone Density - drug effects Bone Density - physiology Bone Development - drug effects Bone Development - physiology Calcium - blood Calcium - urine Calcium, Dietary Creatinine - blood Diet Female Femur - drug effects Femur - physiology Femur - physiopathology Humans In Vitro Techniques Intestinal Absorption Lumbar Vertebrae - drug effects Lumbar Vertebrae - physiology Lumbar Vertebrae - physiopathology Magnesium - blood Magnesium - urine Parathyroid Hormone - pharmacology Peptide Fragments - pharmacology Phosphates - blood Phosphates - urine Phosphorus Rats Rats, Sprague-Dawley Stress, Mechanical Vitamin D - pharmacology Vitamin D Deficiency - metabolism Vitamin D Deficiency - physiopathology
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