Dietary fibers modulate indices of intestinal immune function in rats
To explore the immunological roles of dietary fiber, male 4-wk-old Sprague-Dawley rats were fed for 2 wk cellulose (water-insoluble), konjak mannan (water-soluble), pectin (water-soluble) or chitosan (acid-soluble) at 5 g/100 g diet. Serum IgE concentrations in rats fed konjak mannan, pectin and chi...
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| Veröffentlicht in: | The Journal of nutrition 1997-05, Vol.127 (5), p.663-667 |
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| creator | Lim, B.O Yamada, K Nonaka, M Kuramoto, Y Hung, P Sugano, M |
| description | To explore the immunological roles of dietary fiber, male 4-wk-old Sprague-Dawley rats were fed for 2 wk cellulose (water-insoluble), konjak mannan (water-soluble), pectin (water-soluble) or chitosan (acid-soluble) at 5 g/100 g diet. Serum IgE concentrations in rats fed konjak mannan, pectin and chitosan were significantly lower than in those fed cellulose (mean +/- SEM: 5.0 +/- 1.1, 3.6 +/- 1.3, 3.0 +/- 1.2 and 9.6 +/- 1.9 micrograms/L, respectively). Rats fed pectin had significantly higher serum IgA and IgG concentrations (358 +/- 38 and 424 +/- 36 mg/L for IgA and IgG, respectively) than those fed cellulose (240 +/- 31 and 337 +/- 25 mg/L) or chitosan (176 +/- 22 and 379 +/- 23 mg/L), while the IgM concentration did not differ among the groups. Concentrations of IgA, IgG and IgM in mesenteric lymph node (MLN) lymphocytes generally were greater, while IgE concentration was lower, in rats fed pectin and chitosan than in those fed cellulose. The proportion of CD4+ T-cells in MLN lymphocytes was also dietary fiber-dependent, and the CD4+/CD8+ ratio was significantly higher in the pectin fed group than in all other groups. Under certain experimental conditions, MLN lymphocytes from rats fed pectin had markedly greater interferon-gamma concentration than cells from other groups, while the effect on tumor necrosis factor-alpha concentration was less marked. Thus, dietary fiber may have an immunoregulatory effect on the intestinal immune system of rats |
| doi_str_mv | 10.1093/jn/127.5.663 |
| format | Article |
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Serum IgE concentrations in rats fed konjak mannan, pectin and chitosan were significantly lower than in those fed cellulose (mean +/- SEM: 5.0 +/- 1.1, 3.6 +/- 1.3, 3.0 +/- 1.2 and 9.6 +/- 1.9 micrograms/L, respectively). Rats fed pectin had significantly higher serum IgA and IgG concentrations (358 +/- 38 and 424 +/- 36 mg/L for IgA and IgG, respectively) than those fed cellulose (240 +/- 31 and 337 +/- 25 mg/L) or chitosan (176 +/- 22 and 379 +/- 23 mg/L), while the IgM concentration did not differ among the groups. Concentrations of IgA, IgG and IgM in mesenteric lymph node (MLN) lymphocytes generally were greater, while IgE concentration was lower, in rats fed pectin and chitosan than in those fed cellulose. The proportion of CD4+ T-cells in MLN lymphocytes was also dietary fiber-dependent, and the CD4+/CD8+ ratio was significantly higher in the pectin fed group than in all other groups. Under certain experimental conditions, MLN lymphocytes from rats fed pectin had markedly greater interferon-gamma concentration than cells from other groups, while the effect on tumor necrosis factor-alpha concentration was less marked. Thus, dietary fiber may have an immunoregulatory effect on the intestinal immune system of rats</description><identifier>ISSN: 0022-3166</identifier><identifier>EISSN: 1541-6100</identifier><identifier>DOI: 10.1093/jn/127.5.663</identifier><identifier>PMID: 9164983</identifier><identifier>CODEN: JONUAI</identifier><language>eng</language><publisher>Bethesda, MD: American Society for Nutritional Sciences</publisher><subject>AIDS/HIV ; ANIMAL MODELS ; Animals ; ANTIGENE ; ANTIGENOS ; ANTIGENS ; BAZO ; Biological and medical sciences ; BLOOD SERUM ; CD4 ANTIGENS ; CD4-CD8 Ratio ; CD4-Positive T-Lymphocytes - cytology ; CD4-Positive T-Lymphocytes - metabolism ; CD8 ANTIGENS ; CELLULOSE ; Cellulose - pharmacology ; CELULOSA ; Chitin - analogs & derivatives ; Chitin - pharmacology ; CHITOSAN ; CHITOSANE ; CITOQUINAS ; CYTOKINE ; CYTOKINES ; Cytokines - metabolism ; DIET ; DIETA ; Dietary fiber ; Dietary Fiber - pharmacology ; DIETARY FIBRES ; EXPERIMENTACION ; EXPERIMENTATION ; Feeding. Feeding behavior ; FIBRA DE LA DIETA ; FIBRE ALIMENTAIRE ; Flow Cytometry ; Fundamental and applied biological sciences. Psychology ; Growth - drug effects ; Growth - physiology ; IGA ; IGE ; IGG ; IGM ; IMMUNE RESPONSE ; Immune System - drug effects ; Immune System - physiology ; Immunity (Disease) ; IMMUNOGLOBULINE ; IMMUNOGLOBULINS ; Immunoglobulins - blood ; Immunoglobulins - metabolism ; INMUNOGLOBULINA ; INTERFERON ; Interferon-gamma - analysis ; INTERFERONAS ; INTERFERONS ; Intestines - immunology ; Intestines - metabolism ; Large intestine ; LINFOCITOS ; LYMPHATIC SYSTEM ; LYMPHOCYTE ; LYMPHOCYTES ; Lymphocytes - chemistry ; Lymphocytes - cytology ; Lymphocytes - metabolism ; Male ; Mannose - pharmacology ; MODELE ANIMAL ; MODELOS ANIMALES ; Nutrition ; PECTINAS ; PECTINE ; PECTINS ; Pectins - pharmacology ; QUITOSANO ; RAT ; RATA ; RATE ; RATIOS ; RATS ; Rats, Sprague-Dawley ; REGIME ALIMENTAIRE ; REPONSE IMMUNITAIRE ; RESPUESTA INMUNOLOGICA ; Rodents ; SERUM SANGUIN ; SISTEMA LINFATICO ; Small intestine ; SPLEEN ; SUERO SANGUINEO ; SYSTEME LYMPHATIQUE ; T LYMPHOCYTES ; TUMOR NECROSIS FACTOR ; Tumor Necrosis Factor-alpha - analysis ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>The Journal of nutrition, 1997-05, Vol.127 (5), p.663-667</ispartof><rights>1997 INIST-CNRS</rights><rights>Copyright American Institute of Nutrition May 1997</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-f940140c8ff4c90ae8d44db6b7b087d341b7d6869b2bd9421529fad5236936283</citedby><cites>FETCH-LOGICAL-c468t-f940140c8ff4c90ae8d44db6b7b087d341b7d6869b2bd9421529fad5236936283</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2679472$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9164983$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lim, B.O</creatorcontrib><creatorcontrib>Yamada, K</creatorcontrib><creatorcontrib>Nonaka, M</creatorcontrib><creatorcontrib>Kuramoto, Y</creatorcontrib><creatorcontrib>Hung, P</creatorcontrib><creatorcontrib>Sugano, M</creatorcontrib><title>Dietary fibers modulate indices of intestinal immune function in rats</title><title>The Journal of nutrition</title><addtitle>J Nutr</addtitle><description>To explore the immunological roles of dietary fiber, male 4-wk-old Sprague-Dawley rats were fed for 2 wk cellulose (water-insoluble), konjak mannan (water-soluble), pectin (water-soluble) or chitosan (acid-soluble) at 5 g/100 g diet. Serum IgE concentrations in rats fed konjak mannan, pectin and chitosan were significantly lower than in those fed cellulose (mean +/- SEM: 5.0 +/- 1.1, 3.6 +/- 1.3, 3.0 +/- 1.2 and 9.6 +/- 1.9 micrograms/L, respectively). Rats fed pectin had significantly higher serum IgA and IgG concentrations (358 +/- 38 and 424 +/- 36 mg/L for IgA and IgG, respectively) than those fed cellulose (240 +/- 31 and 337 +/- 25 mg/L) or chitosan (176 +/- 22 and 379 +/- 23 mg/L), while the IgM concentration did not differ among the groups. Concentrations of IgA, IgG and IgM in mesenteric lymph node (MLN) lymphocytes generally were greater, while IgE concentration was lower, in rats fed pectin and chitosan than in those fed cellulose. The proportion of CD4+ T-cells in MLN lymphocytes was also dietary fiber-dependent, and the CD4+/CD8+ ratio was significantly higher in the pectin fed group than in all other groups. Under certain experimental conditions, MLN lymphocytes from rats fed pectin had markedly greater interferon-gamma concentration than cells from other groups, while the effect on tumor necrosis factor-alpha concentration was less marked. Thus, dietary fiber may have an immunoregulatory effect on the intestinal immune system of rats</description><subject>AIDS/HIV</subject><subject>ANIMAL MODELS</subject><subject>Animals</subject><subject>ANTIGENE</subject><subject>ANTIGENOS</subject><subject>ANTIGENS</subject><subject>BAZO</subject><subject>Biological and medical sciences</subject><subject>BLOOD SERUM</subject><subject>CD4 ANTIGENS</subject><subject>CD4-CD8 Ratio</subject><subject>CD4-Positive T-Lymphocytes - cytology</subject><subject>CD4-Positive T-Lymphocytes - metabolism</subject><subject>CD8 ANTIGENS</subject><subject>CELLULOSE</subject><subject>Cellulose - pharmacology</subject><subject>CELULOSA</subject><subject>Chitin - analogs & derivatives</subject><subject>Chitin - pharmacology</subject><subject>CHITOSAN</subject><subject>CHITOSANE</subject><subject>CITOQUINAS</subject><subject>CYTOKINE</subject><subject>CYTOKINES</subject><subject>Cytokines - metabolism</subject><subject>DIET</subject><subject>DIETA</subject><subject>Dietary fiber</subject><subject>Dietary Fiber - pharmacology</subject><subject>DIETARY FIBRES</subject><subject>EXPERIMENTACION</subject><subject>EXPERIMENTATION</subject><subject>Feeding. Feeding behavior</subject><subject>FIBRA DE LA DIETA</subject><subject>FIBRE ALIMENTAIRE</subject><subject>Flow Cytometry</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Growth - drug effects</subject><subject>Growth - physiology</subject><subject>IGA</subject><subject>IGE</subject><subject>IGG</subject><subject>IGM</subject><subject>IMMUNE RESPONSE</subject><subject>Immune System - drug effects</subject><subject>Immune System - physiology</subject><subject>Immunity (Disease)</subject><subject>IMMUNOGLOBULINE</subject><subject>IMMUNOGLOBULINS</subject><subject>Immunoglobulins - blood</subject><subject>Immunoglobulins - metabolism</subject><subject>INMUNOGLOBULINA</subject><subject>INTERFERON</subject><subject>Interferon-gamma - analysis</subject><subject>INTERFERONAS</subject><subject>INTERFERONS</subject><subject>Intestines - immunology</subject><subject>Intestines - metabolism</subject><subject>Large intestine</subject><subject>LINFOCITOS</subject><subject>LYMPHATIC SYSTEM</subject><subject>LYMPHOCYTE</subject><subject>LYMPHOCYTES</subject><subject>Lymphocytes - chemistry</subject><subject>Lymphocytes - cytology</subject><subject>Lymphocytes - metabolism</subject><subject>Male</subject><subject>Mannose - pharmacology</subject><subject>MODELE ANIMAL</subject><subject>MODELOS ANIMALES</subject><subject>Nutrition</subject><subject>PECTINAS</subject><subject>PECTINE</subject><subject>PECTINS</subject><subject>Pectins - pharmacology</subject><subject>QUITOSANO</subject><subject>RAT</subject><subject>RATA</subject><subject>RATE</subject><subject>RATIOS</subject><subject>RATS</subject><subject>Rats, Sprague-Dawley</subject><subject>REGIME ALIMENTAIRE</subject><subject>REPONSE IMMUNITAIRE</subject><subject>RESPUESTA INMUNOLOGICA</subject><subject>Rodents</subject><subject>SERUM SANGUIN</subject><subject>SISTEMA LINFATICO</subject><subject>Small intestine</subject><subject>SPLEEN</subject><subject>SUERO SANGUINEO</subject><subject>SYSTEME LYMPHATIQUE</subject><subject>T LYMPHOCYTES</subject><subject>TUMOR NECROSIS FACTOR</subject><subject>Tumor Necrosis Factor-alpha - analysis</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0022-3166</issn><issn>1541-6100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtLxTAQRoMoen3s3ApFxJW95tVJsxS9PkBwoa5Dmofk0qaatAv_vREvCq5m4Dt8zByEjgleEizZ5TpeEiqWzRKAbaEFaTipgWC8jRYYU1ozArCH9nNeY4wJl-0u2pUEysIWaHUT3KTTZ-VD51KuhtHOvZ5cFaINxuVq9GWdXJ5C1H0VhmGOrvJzNFMYY4mqpKd8iHa87rM72swD9Hq7erm-rx-f7h6urx5rw6Gdai95OQCb1ntuJNautZzbDjrR4VZYxkknLLQgO9pZySlpqPTaNpSBZEBbdoDOf3rf0_gxl6PUELJxfa-jG-eshMRMSAoFPP0Hrsc5lQ-yIlJwBsC_2y5-IJPGnJPz6j2FochQBKtvtWodVVGrGlXUFvxk0zl3g7O_8MZlyc82uc5G9z7paEL-xSgIyQX9q_F6VPotFeT1mUgpMAARgn0BFuqIWw</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Lim, B.O</creator><creator>Yamada, K</creator><creator>Nonaka, M</creator><creator>Kuramoto, Y</creator><creator>Hung, P</creator><creator>Sugano, M</creator><general>American Society for Nutritional Sciences</general><general>American Institute of Nutrition</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>19970501</creationdate><title>Dietary fibers modulate indices of intestinal immune function in rats</title><author>Lim, B.O ; Yamada, K ; Nonaka, M ; Kuramoto, Y ; Hung, P ; Sugano, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-f940140c8ff4c90ae8d44db6b7b087d341b7d6869b2bd9421529fad5236936283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>AIDS/HIV</topic><topic>ANIMAL MODELS</topic><topic>Animals</topic><topic>ANTIGENE</topic><topic>ANTIGENOS</topic><topic>ANTIGENS</topic><topic>BAZO</topic><topic>Biological and medical sciences</topic><topic>BLOOD SERUM</topic><topic>CD4 ANTIGENS</topic><topic>CD4-CD8 Ratio</topic><topic>CD4-Positive T-Lymphocytes - cytology</topic><topic>CD4-Positive T-Lymphocytes - metabolism</topic><topic>CD8 ANTIGENS</topic><topic>CELLULOSE</topic><topic>Cellulose - pharmacology</topic><topic>CELULOSA</topic><topic>Chitin - analogs & derivatives</topic><topic>Chitin - pharmacology</topic><topic>CHITOSAN</topic><topic>CHITOSANE</topic><topic>CITOQUINAS</topic><topic>CYTOKINE</topic><topic>CYTOKINES</topic><topic>Cytokines - metabolism</topic><topic>DIET</topic><topic>DIETA</topic><topic>Dietary fiber</topic><topic>Dietary Fiber - pharmacology</topic><topic>DIETARY FIBRES</topic><topic>EXPERIMENTACION</topic><topic>EXPERIMENTATION</topic><topic>Feeding. Feeding behavior</topic><topic>FIBRA DE LA DIETA</topic><topic>FIBRE ALIMENTAIRE</topic><topic>Flow Cytometry</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Growth - drug effects</topic><topic>Growth - physiology</topic><topic>IGA</topic><topic>IGE</topic><topic>IGG</topic><topic>IGM</topic><topic>IMMUNE RESPONSE</topic><topic>Immune System - drug effects</topic><topic>Immune System - physiology</topic><topic>Immunity (Disease)</topic><topic>IMMUNOGLOBULINE</topic><topic>IMMUNOGLOBULINS</topic><topic>Immunoglobulins - blood</topic><topic>Immunoglobulins - metabolism</topic><topic>INMUNOGLOBULINA</topic><topic>INTERFERON</topic><topic>Interferon-gamma - analysis</topic><topic>INTERFERONAS</topic><topic>INTERFERONS</topic><topic>Intestines - immunology</topic><topic>Intestines - metabolism</topic><topic>Large intestine</topic><topic>LINFOCITOS</topic><topic>LYMPHATIC SYSTEM</topic><topic>LYMPHOCYTE</topic><topic>LYMPHOCYTES</topic><topic>Lymphocytes - chemistry</topic><topic>Lymphocytes - cytology</topic><topic>Lymphocytes - metabolism</topic><topic>Male</topic><topic>Mannose - pharmacology</topic><topic>MODELE ANIMAL</topic><topic>MODELOS ANIMALES</topic><topic>Nutrition</topic><topic>PECTINAS</topic><topic>PECTINE</topic><topic>PECTINS</topic><topic>Pectins - pharmacology</topic><topic>QUITOSANO</topic><topic>RAT</topic><topic>RATA</topic><topic>RATE</topic><topic>RATIOS</topic><topic>RATS</topic><topic>Rats, Sprague-Dawley</topic><topic>REGIME ALIMENTAIRE</topic><topic>REPONSE IMMUNITAIRE</topic><topic>RESPUESTA INMUNOLOGICA</topic><topic>Rodents</topic><topic>SERUM SANGUIN</topic><topic>SISTEMA LINFATICO</topic><topic>Small intestine</topic><topic>SPLEEN</topic><topic>SUERO SANGUINEO</topic><topic>SYSTEME LYMPHATIQUE</topic><topic>T LYMPHOCYTES</topic><topic>TUMOR NECROSIS FACTOR</topic><topic>Tumor Necrosis Factor-alpha - analysis</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lim, B.O</creatorcontrib><creatorcontrib>Yamada, K</creatorcontrib><creatorcontrib>Nonaka, M</creatorcontrib><creatorcontrib>Kuramoto, Y</creatorcontrib><creatorcontrib>Hung, P</creatorcontrib><creatorcontrib>Sugano, M</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lim, B.O</au><au>Yamada, K</au><au>Nonaka, M</au><au>Kuramoto, Y</au><au>Hung, P</au><au>Sugano, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary fibers modulate indices of intestinal immune function in rats</atitle><jtitle>The Journal of nutrition</jtitle><addtitle>J Nutr</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>127</volume><issue>5</issue><spage>663</spage><epage>667</epage><pages>663-667</pages><issn>0022-3166</issn><eissn>1541-6100</eissn><coden>JONUAI</coden><abstract>To explore the immunological roles of dietary fiber, male 4-wk-old Sprague-Dawley rats were fed for 2 wk cellulose (water-insoluble), konjak mannan (water-soluble), pectin (water-soluble) or chitosan (acid-soluble) at 5 g/100 g diet. Serum IgE concentrations in rats fed konjak mannan, pectin and chitosan were significantly lower than in those fed cellulose (mean +/- SEM: 5.0 +/- 1.1, 3.6 +/- 1.3, 3.0 +/- 1.2 and 9.6 +/- 1.9 micrograms/L, respectively). Rats fed pectin had significantly higher serum IgA and IgG concentrations (358 +/- 38 and 424 +/- 36 mg/L for IgA and IgG, respectively) than those fed cellulose (240 +/- 31 and 337 +/- 25 mg/L) or chitosan (176 +/- 22 and 379 +/- 23 mg/L), while the IgM concentration did not differ among the groups. Concentrations of IgA, IgG and IgM in mesenteric lymph node (MLN) lymphocytes generally were greater, while IgE concentration was lower, in rats fed pectin and chitosan than in those fed cellulose. The proportion of CD4+ T-cells in MLN lymphocytes was also dietary fiber-dependent, and the CD4+/CD8+ ratio was significantly higher in the pectin fed group than in all other groups. Under certain experimental conditions, MLN lymphocytes from rats fed pectin had markedly greater interferon-gamma concentration than cells from other groups, while the effect on tumor necrosis factor-alpha concentration was less marked. Thus, dietary fiber may have an immunoregulatory effect on the intestinal immune system of rats</abstract><cop>Bethesda, MD</cop><pub>American Society for Nutritional Sciences</pub><pmid>9164983</pmid><doi>10.1093/jn/127.5.663</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The Journal of nutrition, 1997-05, Vol.127 (5), p.663-667 |
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| subjects | AIDS/HIV ANIMAL MODELS Animals ANTIGENE ANTIGENOS ANTIGENS BAZO Biological and medical sciences BLOOD SERUM CD4 ANTIGENS CD4-CD8 Ratio CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - metabolism CD8 ANTIGENS CELLULOSE Cellulose - pharmacology CELULOSA Chitin - analogs & derivatives Chitin - pharmacology CHITOSAN CHITOSANE CITOQUINAS CYTOKINE CYTOKINES Cytokines - metabolism DIET DIETA Dietary fiber Dietary Fiber - pharmacology DIETARY FIBRES EXPERIMENTACION EXPERIMENTATION Feeding. Feeding behavior FIBRA DE LA DIETA FIBRE ALIMENTAIRE Flow Cytometry Fundamental and applied biological sciences. Psychology Growth - drug effects Growth - physiology IGA IGE IGG IGM IMMUNE RESPONSE Immune System - drug effects Immune System - physiology Immunity (Disease) IMMUNOGLOBULINE IMMUNOGLOBULINS Immunoglobulins - blood Immunoglobulins - metabolism INMUNOGLOBULINA INTERFERON Interferon-gamma - analysis INTERFERONAS INTERFERONS Intestines - immunology Intestines - metabolism Large intestine LINFOCITOS LYMPHATIC SYSTEM LYMPHOCYTE LYMPHOCYTES Lymphocytes - chemistry Lymphocytes - cytology Lymphocytes - metabolism Male Mannose - pharmacology MODELE ANIMAL MODELOS ANIMALES Nutrition PECTINAS PECTINE PECTINS Pectins - pharmacology QUITOSANO RAT RATA RATE RATIOS RATS Rats, Sprague-Dawley REGIME ALIMENTAIRE REPONSE IMMUNITAIRE RESPUESTA INMUNOLOGICA Rodents SERUM SANGUIN SISTEMA LINFATICO Small intestine SPLEEN SUERO SANGUINEO SYSTEME LYMPHATIQUE T LYMPHOCYTES TUMOR NECROSIS FACTOR Tumor Necrosis Factor-alpha - analysis Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Dietary fibers modulate indices of intestinal immune function in rats |
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