Nutritional status and psychometric test scores in cognitively impaired elders
In a pilot study, we compared dietary and biochemical status for vitamin B1, B2, B12, and C and folate, iron, and protein in CI and CN elders grouped by MMSE scores. Biochemical evaluation of folate and B12 status was continued beyond the preliminary study. Intakes of all nutrients except folate exc...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 1989, Vol.561 (1), p.167-177 |
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| container_title | Annals of the New York Academy of Sciences |
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| creator | Spindler, A.A. (San Diego State University, San Diego, CA) Renvall, M.A |
| description | In a pilot study, we compared dietary and biochemical status for vitamin B1, B2, B12, and C and folate, iron, and protein in CI and CN elders grouped by MMSE scores. Biochemical evaluation of folate and B12 status was continued beyond the preliminary study. Intakes of all nutrients except folate exceeded 66% of the RDA. There were no significant differences among MMSE groups for dietary intake or biochemical values. Transketolase activity increased with degree of impairment, whereas measures for the other vitamins declined. Low or deficient LAA levels were found in 33% of all elders. Folate and B12 deficiencies, respectively, were found in 11% (12/109) and 4% (10/254) of the population. Very low values for serum B12 (less than 250 pg/ml) existed in 15% (37/254) of the subjects (31 CI; 7 CN). Moderately impaired elders (MMSE = 15-20) who used multivitamin supplements had RBC folate (p less than .003) and serum B12 (p less than .02) levels higher than those of subjects who did not use supplements. |
| doi_str_mv | 10.1111/j.1749-6632.1989.tb20980.x |
| format | Article |
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Moderately impaired elders (MMSE = 15-20) who used multivitamin supplements had RBC folate (p less than .003) and serum B12 (p less than .02) levels higher than those of subjects who did not use supplements.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/j.1749-6632.1989.tb20980.x</identifier><identifier>PMID: 2735676</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aged ; Aged, 80 and over ; Avitaminosis - metabolism ; Blood Chemical Analysis ; Cognition Disorders - physiopathology ; COGNITIVE DEVELOPMENT ; DEFICIENCY DISEASES ; Energy Intake ; ENFERMEDADES CARENCIALES ; ENSAYO ; ESTADO NUTRICIONAL ; ESTADOS UNIDOS DE AMERICA ; ETAT NUTRITIONNEL ; ETATS-UNIS ; Female ; Humans ; MALADIE DE CARENCE ; Male ; MALNUTRICION ; MALNUTRITION ; MENTAL DISORDERS ; NERVOUS SYSTEM DISEASES ; NUTRITIONAL STATUS ; Psychometrics ; TESTAGE ; TESTING ; TRASTORNOS DEL SISTEMA NERVIOSO ; TROUBLE DU SYSTEME NERVEUX ; USA ; Vitamins - administration & dosage</subject><ispartof>Annals of the New York Academy of Sciences, 1989, Vol.561 (1), p.167-177</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-576f78813a4e652e833dcc01c2576f0da0e801d1badafdcf24aaa2b7e17f10193</citedby><cites>FETCH-LOGICAL-c371t-576f78813a4e652e833dcc01c2576f0da0e801d1badafdcf24aaa2b7e17f10193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2735676$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spindler, A.A. (San Diego State University, San Diego, CA)</creatorcontrib><creatorcontrib>Renvall, M.A</creatorcontrib><title>Nutritional status and psychometric test scores in cognitively impaired elders</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>In a pilot study, we compared dietary and biochemical status for vitamin B1, B2, B12, and C and folate, iron, and protein in CI and CN elders grouped by MMSE scores. Biochemical evaluation of folate and B12 status was continued beyond the preliminary study. Intakes of all nutrients except folate exceeded 66% of the RDA. There were no significant differences among MMSE groups for dietary intake or biochemical values. Transketolase activity increased with degree of impairment, whereas measures for the other vitamins declined. Low or deficient LAA levels were found in 33% of all elders. Folate and B12 deficiencies, respectively, were found in 11% (12/109) and 4% (10/254) of the population. Very low values for serum B12 (less than 250 pg/ml) existed in 15% (37/254) of the subjects (31 CI; 7 CN). Moderately impaired elders (MMSE = 15-20) who used multivitamin supplements had RBC folate (p less than .003) and serum B12 (p less than .02) levels higher than those of subjects who did not use supplements.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Avitaminosis - metabolism</subject><subject>Blood Chemical Analysis</subject><subject>Cognition Disorders - physiopathology</subject><subject>COGNITIVE DEVELOPMENT</subject><subject>DEFICIENCY DISEASES</subject><subject>Energy Intake</subject><subject>ENFERMEDADES CARENCIALES</subject><subject>ENSAYO</subject><subject>ESTADO NUTRICIONAL</subject><subject>ESTADOS UNIDOS DE AMERICA</subject><subject>ETAT NUTRITIONNEL</subject><subject>ETATS-UNIS</subject><subject>Female</subject><subject>Humans</subject><subject>MALADIE DE CARENCE</subject><subject>Male</subject><subject>MALNUTRICION</subject><subject>MALNUTRITION</subject><subject>MENTAL DISORDERS</subject><subject>NERVOUS SYSTEM DISEASES</subject><subject>NUTRITIONAL STATUS</subject><subject>Psychometrics</subject><subject>TESTAGE</subject><subject>TESTING</subject><subject>TRASTORNOS DEL SISTEMA NERVIOSO</subject><subject>TROUBLE DU SYSTEME NERVEUX</subject><subject>USA</subject><subject>Vitamins - administration & dosage</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtvEzEURi1EVdLCH0BCsliwm8GPxA92ELUFKUoXpQKxsRz7TnGYR2p7quTf41GieHMX5_uurw5CHympaXmftzWVc10JwVlNtdJ13jCiFan3r9DsjF6jGSFSVkoz_gZdpbQlhDI1l5fokkm-EFLM0Ho95hhyGHrb4pRtHhO2vce7dHB_hw4KdDhDyji5IULCocdueOpL5QXaAw7dzoYIHkPrIaa36KKxbYJ3p3mNHm9vfi6_V6v7ux_Lr6vKcUlztZCikUpRbucgFgwU5945Qh2bCPGWgCLU0431tvGuYXNrLdtIoLKhhGp-jT4d9-7i8DyW80wXkoO2tT0MYzJSEy6EoCX45Rh0cUgpQmN2MXQ2HgwlZpJptmYyZiZjZpJpTjLNvpQ_nH4ZNx34c_Vkr_DqyEPKsD9jG_8ZIblcmF_rO_Pn24NYyeVvo0r-_THf2MHYpxiSeXzQhOiS5v8Ba_2K7A</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Spindler, A.A. (San Diego State University, San Diego, CA)</creator><creator>Renvall, M.A</creator><general>Blackwell Publishing Ltd</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>Nutritional status and psychometric test scores in cognitively impaired elders</title><author>Spindler, A.A. (San Diego State University, San Diego, CA) ; Renvall, M.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-576f78813a4e652e833dcc01c2576f0da0e801d1badafdcf24aaa2b7e17f10193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Avitaminosis - metabolism</topic><topic>Blood Chemical Analysis</topic><topic>Cognition Disorders - physiopathology</topic><topic>COGNITIVE DEVELOPMENT</topic><topic>DEFICIENCY DISEASES</topic><topic>Energy Intake</topic><topic>ENFERMEDADES CARENCIALES</topic><topic>ENSAYO</topic><topic>ESTADO NUTRICIONAL</topic><topic>ESTADOS UNIDOS DE AMERICA</topic><topic>ETAT NUTRITIONNEL</topic><topic>ETATS-UNIS</topic><topic>Female</topic><topic>Humans</topic><topic>MALADIE DE CARENCE</topic><topic>Male</topic><topic>MALNUTRICION</topic><topic>MALNUTRITION</topic><topic>MENTAL DISORDERS</topic><topic>NERVOUS SYSTEM DISEASES</topic><topic>NUTRITIONAL STATUS</topic><topic>Psychometrics</topic><topic>TESTAGE</topic><topic>TESTING</topic><topic>TRASTORNOS DEL SISTEMA NERVIOSO</topic><topic>TROUBLE DU SYSTEME NERVEUX</topic><topic>USA</topic><topic>Vitamins - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spindler, A.A. (San Diego State University, San Diego, CA)</creatorcontrib><creatorcontrib>Renvall, M.A</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spindler, A.A. (San Diego State University, San Diego, CA)</au><au>Renvall, M.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nutritional status and psychometric test scores in cognitively impaired elders</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>1989</date><risdate>1989</risdate><volume>561</volume><issue>1</issue><spage>167</spage><epage>177</epage><pages>167-177</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><abstract>In a pilot study, we compared dietary and biochemical status for vitamin B1, B2, B12, and C and folate, iron, and protein in CI and CN elders grouped by MMSE scores. Biochemical evaluation of folate and B12 status was continued beyond the preliminary study. Intakes of all nutrients except folate exceeded 66% of the RDA. There were no significant differences among MMSE groups for dietary intake or biochemical values. Transketolase activity increased with degree of impairment, whereas measures for the other vitamins declined. Low or deficient LAA levels were found in 33% of all elders. Folate and B12 deficiencies, respectively, were found in 11% (12/109) and 4% (10/254) of the population. Very low values for serum B12 (less than 250 pg/ml) existed in 15% (37/254) of the subjects (31 CI; 7 CN). Moderately impaired elders (MMSE = 15-20) who used multivitamin supplements had RBC folate (p less than .003) and serum B12 (p less than .02) levels higher than those of subjects who did not use supplements.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2735676</pmid><doi>10.1111/j.1749-6632.1989.tb20980.x</doi><tpages>11</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Aged, 80 and over Avitaminosis - metabolism Blood Chemical Analysis Cognition Disorders - physiopathology COGNITIVE DEVELOPMENT DEFICIENCY DISEASES Energy Intake ENFERMEDADES CARENCIALES ENSAYO ESTADO NUTRICIONAL ESTADOS UNIDOS DE AMERICA ETAT NUTRITIONNEL ETATS-UNIS Female Humans MALADIE DE CARENCE Male MALNUTRICION MALNUTRITION MENTAL DISORDERS NERVOUS SYSTEM DISEASES NUTRITIONAL STATUS Psychometrics TESTAGE TESTING TRASTORNOS DEL SISTEMA NERVIOSO TROUBLE DU SYSTEME NERVEUX USA Vitamins - administration & dosage |
| title | Nutritional status and psychometric test scores in cognitively impaired elders |
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