Platelet Glycoprotein IIb/IIIa Receptor Blockade and Low-Dose Heparin during Percutaneous Coronary Revascularization

New strategies for preventing ischemic complications during percutaneous coronary revascularization have focused on the platelet surface-membrane glycoprotein IIb/IIIa receptor. 1 In a previous large-scale trial (Evaluation of 7E3 for the Prevention of Ischemic Complications, or EPIC), blockade of t...

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Veröffentlicht in:	The New England journal of medicine 1997-06, Vol.336 (24), p.1689-1697
Hauptverfasser:	Topol, E J, Califf, R M, Lincoff, A M, Tcheng, J E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angioplasty Angioplasty, Balloon, Coronary - adverse effects Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Anticoagulants - administration & dosage Biological and medical sciences Blood pressure Blood. Blood coagulation. Reticuloendothelial system Coronary Disease - mortality Coronary Disease - therapy Double-Blind Method Drug therapy Female Heart attacks Hemorrhage - chemically induced Hemorrhage - prevention & control Heparin - administration & dosage Humans Immunoglobulin Fab Fragments - adverse effects Immunoglobulin Fab Fragments - therapeutic use Male Medical sciences Middle Aged Myocardial Infarction - epidemiology Myocardial Ischemia - etiology Myocardial Ischemia - prevention & control Myocardial Ischemia - therapy Pharmacology. Drug treatments Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - therapeutic use Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors Prospective Studies
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