A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma

A novel human gene CC3 with properties of a metastasis suppresor gene for small cell lung carcinoma (SCLC) is described. CC3 is an evolutionary conserved gene that is expressed ubiquitously in human tissues. CC3 RNA is absent in a subset of SCLC cell lines known as variant (v-SCLC) that are derived...

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Veröffentlicht in:	Oncogene 1997-05, Vol.14 (18), p.2167-2173
1. Verfasser:	Shtivelman, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apoptosis Apoptosis - genetics Blotting, Northern Carcinoma, Small Cell - genetics Carcinoma, Small Cell - pathology Carcinoma, Small Cell - secretion Cell death Cell Division - genetics Evolutionary conservation Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor Growth factors Humans Lung cancer Lung carcinoma Metastases Metastasis Mice Mice, SCID Molecular Sequence Data Neoplasm Invasiveness - genetics Sequence Homology, Amino Acid Small cell lung carcinoma Tissue Distribution Tumor Cells, Cultured Tumors
Online-Zugang:	Volltext
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