Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation

Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis. Severe fibrinolysis was defined to be present...

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Veröffentlicht in:	Transplantation 1989-06, Vol.47 (6), p.978-984
Hauptverfasser:	PORTE, R. J, BONTEMPO, F. A, KNOT, E. A. R, LEWIS, J. H, YOO GOO KANG, STARZL, T. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antithrombin III - metabolism Biological and medical sciences Blood Transfusion Female Fibrin Fibrinogen Degradation Products - metabolism Fibrinolysis Hemodynamics Humans Intraoperative Period Liver - physiopathology Liver Transplantation Liver, biliary tract, pancreas, portal circulation, spleen Male Medical sciences Middle Aged Prospective Studies Serum Globulins Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Thrombin - biosynthesis Tissue Plasminogen Activator - physiology Whole Blood Coagulation Time
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