Trypanosoma cruzi reduces the number of high-affinity IL-2 receptors on activated human lymphocytes by suppressing the expression of the p55 and p70 receptor components

We previously established that Trypanosoma cruzi, the causative agent of Chagas' disease, has the ability to suppress expression of the p55 component of the IL-2R by activated human PBMC. We explored in this work whether the parasite alters the expression of high affinity IL-2R, responsible for...

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Veröffentlicht in:The Journal of immunology (1950) 1989-07, Vol.143 (1), p.275-279
Hauptverfasser: Kierszenbaum, F, Cuna, WR, Beltz, LA, Sztein, MB
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Sprache:eng
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