Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation

During neural crest development in avian embryos, transcription factor N-myc is initially expressed in the entire cell population. The expression is then turned off in the period following colonization in ganglion and nerve cord areas except for the cells undergoing neuronal differentiation. This wa...

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Veröffentlicht in:	Development (Cambridge) 1997-05, Vol.124 (10), p.1953-1962
Hauptverfasser:	Wakamatsu, Y, Watanabe, Y, Nakamura, H, Kondoh, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Cell Movement - physiology Cells, Cultured Chick Embryo Chimera Coturnix - embryology Coturnix - genetics Ganglia, Spinal - cytology Ganglia, Sympathetic - cytology Gene Expression Regulation, Developmental Genes, myc - physiology Molecular Sequence Data Neural Crest - chemistry Neural Crest - cytology Neural Crest - transplantation Neurons - chemistry Proto-Oncogene Proteins c-myc - analysis Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - physiology Transfection
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