Augmented intracellular glutathione inhibits fas-triggered apoptosis of activated human neutrophils

Agonist signals delivered through cell surface Fas induce apoptosis. However, the apoptotic program can be modulated by signals from the environment, and in particular, by signals delivered through adhesion molecules. Because neutrophil functional activity in inflammation is contingent on cell survi...

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Veröffentlicht in:	Blood 1997-06, Vol.89 (11), p.4175-4181
Hauptverfasser:	WATSON, R. W. G, ROTSTEIN, O. D, JIMENEZ, M, PARODO, J, MARSHALL, J. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Apoptosis - physiology Biological and medical sciences Cell physiology Cells, Cultured fas Receptor - physiology Fundamental and applied biological sciences. Psychology Glutathione - physiology Humans Lipopolysaccharides - pharmacology Molecular and cellular biology Neutrophil Activation - drug effects Neutrophils - pathology Neutrophils - physiology
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