The role of ERCP in biliary atresia

Background: It is not easy to discriminate between infantile hepatitis and biliary atresia in spite of several diagnostic tests including laboratory analyses, ultrasound, and hepatobiliary scans. ERCP is the most useful procedure for visualization of the extrahepatic biliary system, but ERCP is stil...

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Veröffentlicht in:Gastrointestinal endoscopy 1997-05, Vol.45 (5), p.365-370
Hauptverfasser: Ohnuma, Naomi, Takahashi, Hideyo, Tanabe, Masahiro, Yoshida, Hideo, Iwai, Jun
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container_end_page 370
container_issue 5
container_start_page 365
container_title Gastrointestinal endoscopy
container_volume 45
creator Ohnuma, Naomi
Takahashi, Hideyo
Tanabe, Masahiro
Yoshida, Hideo
Iwai, Jun
description Background: It is not easy to discriminate between infantile hepatitis and biliary atresia in spite of several diagnostic tests including laboratory analyses, ultrasound, and hepatobiliary scans. ERCP is the most useful procedure for visualization of the extrahepatic biliary system, but ERCP is still an uncommon procedure in children. Methods: ERCP examination was performed in 52 infants with biliary atresia (10 with infantile hepatitis, 5 with congenital biliary dilatation, 3 with paucity of intrahepatic bile duct, 2 with duodenal atresia, and 1 with postoperative jaundice of hepatoblastoma) aged from 8 days to 300 days (mean, 71 days). Results: ERCP was successful in 47 with biliary atresia, in 9 with infantile hepatitis, and 10 with another disease. Liver biopsy was performed in 1 infant with hepatitis in whom the cannulation failed; in 9 with hepatitis in whom the cannulation was successful, exploratory laparotomy could be avoided. The ERCP findings in 46 patients with biliary atresia (excluding 1 in whom evaluation could not be performed because of poor x-ray quality) were classified into four patterns. Conclusions: A success rate of ERCP examinations in infants was 88%, so ERCP is recommended to make a correct decision regarding the need for surgery in cholestatic disorders. (Gastrintest Endosc 1997;45:365-70.)
doi_str_mv 10.1016/S0016-5107(97)70145-7
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ERCP is the most useful procedure for visualization of the extrahepatic biliary system, but ERCP is still an uncommon procedure in children. Methods: ERCP examination was performed in 52 infants with biliary atresia (10 with infantile hepatitis, 5 with congenital biliary dilatation, 3 with paucity of intrahepatic bile duct, 2 with duodenal atresia, and 1 with postoperative jaundice of hepatoblastoma) aged from 8 days to 300 days (mean, 71 days). Results: ERCP was successful in 47 with biliary atresia, in 9 with infantile hepatitis, and 10 with another disease. Liver biopsy was performed in 1 infant with hepatitis in whom the cannulation failed; in 9 with hepatitis in whom the cannulation was successful, exploratory laparotomy could be avoided. The ERCP findings in 46 patients with biliary atresia (excluding 1 in whom evaluation could not be performed because of poor x-ray quality) were classified into four patterns. 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ERCP is the most useful procedure for visualization of the extrahepatic biliary system, but ERCP is still an uncommon procedure in children. Methods: ERCP examination was performed in 52 infants with biliary atresia (10 with infantile hepatitis, 5 with congenital biliary dilatation, 3 with paucity of intrahepatic bile duct, 2 with duodenal atresia, and 1 with postoperative jaundice of hepatoblastoma) aged from 8 days to 300 days (mean, 71 days). Results: ERCP was successful in 47 with biliary atresia, in 9 with infantile hepatitis, and 10 with another disease. Liver biopsy was performed in 1 infant with hepatitis in whom the cannulation failed; in 9 with hepatitis in whom the cannulation was successful, exploratory laparotomy could be avoided. The ERCP findings in 46 patients with biliary atresia (excluding 1 in whom evaluation could not be performed because of poor x-ray quality) were classified into four patterns. 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Abdomen</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Hepatitis - diagnostic imaging</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><issn>0016-5107</issn><issn>1097-6779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVZ_QmFBET2s5mN3JzmJlPoBBUXrOcxmsxjZ7tZkK_jvTT_o1UvmMM87mXkIGTN6wygrbt9pfNOcUbhScA2UZXkKB2TIqIK0AFCHZLhHjslJCF-UUskFG5CBYkUuWDEk5_NPm_iusUlXJ9O3yWvi2qR0jUP_m2DvbXB4So5qbII929UR-XiYzidP6ezl8XlyP0uNkKpPcwUiQ5FLi8A5YobMlFBWosaaU8gAgNeKSY6ViRylSonMADdVCTlKKUbkcjt36bvvlQ29XrhgbNNga7tV0KBiRhYigvkWNL4LwdtaL71bxI01o3otR2_k6PXlWoHeyNEQc-PdB6tyYat9amcj9i92fQwGm9pja1zYY7woJGRZxO62mI0yfpz1OhhnW2Mr563pddW5fxb5A5ZzfXk</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Ohnuma, Naomi</creator><creator>Takahashi, Hideyo</creator><creator>Tanabe, Masahiro</creator><creator>Yoshida, Hideo</creator><creator>Iwai, Jun</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19970501</creationdate><title>The role of ERCP in biliary atresia</title><author>Ohnuma, Naomi ; Takahashi, Hideyo ; Tanabe, Masahiro ; Yoshida, Hideo ; Iwai, Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-59734a358ea722aa4a1cb7bd3faf20747772f9182adc4a3009934c72cdb75a883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Biliary Atresia - classification</topic><topic>Biliary Atresia - diagnostic imaging</topic><topic>Biological and medical sciences</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - instrumentation</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - methods</topic><topic>Common Bile Duct - diagnostic imaging</topic><topic>Contrast Media</topic><topic>Diagnosis, Differential</topic><topic>Diatrizoate Meglumine</topic><topic>Digestive system. Abdomen</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Hepatitis - diagnostic imaging</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ohnuma, Naomi</creatorcontrib><creatorcontrib>Takahashi, Hideyo</creatorcontrib><creatorcontrib>Tanabe, Masahiro</creatorcontrib><creatorcontrib>Yoshida, Hideo</creatorcontrib><creatorcontrib>Iwai, Jun</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastrointestinal endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ohnuma, Naomi</au><au>Takahashi, Hideyo</au><au>Tanabe, Masahiro</au><au>Yoshida, Hideo</au><au>Iwai, Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of ERCP in biliary atresia</atitle><jtitle>Gastrointestinal endoscopy</jtitle><addtitle>Gastrointest Endosc</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>45</volume><issue>5</issue><spage>365</spage><epage>370</epage><pages>365-370</pages><issn>0016-5107</issn><eissn>1097-6779</eissn><coden>GAENBQ</coden><abstract>Background: It is not easy to discriminate between infantile hepatitis and biliary atresia in spite of several diagnostic tests including laboratory analyses, ultrasound, and hepatobiliary scans. 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subjects Biliary Atresia - classification
Biliary Atresia - diagnostic imaging
Biological and medical sciences
Cholangiopancreatography, Endoscopic Retrograde - instrumentation
Cholangiopancreatography, Endoscopic Retrograde - methods
Common Bile Duct - diagnostic imaging
Contrast Media
Diagnosis, Differential
Diatrizoate Meglumine
Digestive system. Abdomen
Endoscopy
Female
Hepatitis - diagnostic imaging
Humans
Infant
Infant, Newborn
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
title The role of ERCP in biliary atresia
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