Oestrogen and progesterone receptors and their relationship to histological grades of epithelial tumours of the magnum region of the oviduct of the domestic fowl
Tumours of the proprial tubular glands of the magnum region of the oviduct of the domestic fowl ( Gallus domesticus) were found to contain receptors for oestrogen and progesterone. The distribution of the receptors in the cytosol and nucleus of the tumour cells was similar to that of the normal magn...
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| Veröffentlicht in: | Journal of comparative pathology 1989-04, Vol.100 (3), p.275-286 |
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| container_end_page | 286 |
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| container_title | Journal of comparative pathology |
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| creator | Anjum, A.D. Payne, L.N. Appleby, E.C. |
| description | Tumours of the proprial tubular glands of the magnum region of the oviduct of the domestic fowl (
Gallus domesticus) were found to contain receptors for oestrogen and progesterone. The distribution of the receptors in the cytosol and nucleus of the tumour cells was similar to that of the normal magnum under oestrogen stimulation. Receptor content showed a positive correlation with increasing clinical stage and histological grade, i.e., malignancy and undifferentiation of the tumours. These tumours are unusual for hormonally responsive tumours in that their receptor mechanism remains intact with loss of differentiation. |
| doi_str_mv | 10.1016/0021-9975(89)90105-9 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0021-9975 |
| ispartof | Journal of comparative pathology, 1989-04, Vol.100 (3), p.275-286 |
| issn | 0021-9975 1532-3129 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79005197 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Chickens Estrogens - metabolism Female Neoplasms - analysis Neoplasms - pathology Neoplasms - veterinary Oviducts - analysis Poultry Diseases - metabolism Poultry Diseases - pathology Progesterone - metabolism Receptors, Estrogen - analysis Receptors, Progesterone - analysis |
| title | Oestrogen and progesterone receptors and their relationship to histological grades of epithelial tumours of the magnum region of the oviduct of the domestic fowl |
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