Fasting gastric fluid and fecal polyamine concentrations in premature infants
Background: The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid...
Gespeichert in:
| Veröffentlicht in: | Journal of pediatric gastroenterology and nutrition 1997-04, Vol.24 (4), p.389-392 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 392 |
|---|---|
| container_issue | 4 |
| container_start_page | 389 |
| container_title | Journal of pediatric gastroenterology and nutrition |
| container_volume | 24 |
| creator | Forget, P.P Degraeuwe, P.L.J Smeets, C Deutz, N.E.P |
| description | Background: The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid and fecal polyamine concentrations in premature infants during the postnatal period. We further compared gastric fluid polyamine concentrations with those reported for milk and looked for possible relationships between luminal polyamine concentrations, age, and growth rate. Methods: High-performance liquid chromatography was used for the measurement of polyamine concentrations in both fecal and gastric fluid samples. Results: Ninetieth centiles for gastric polyamines during the first week were 62, 28, 82, and 14 micromolar for putrescine, spermidine, spermine, and cadaverine, respectively. These values are higher than those reported for human milk and infant formulas. Polyamine concentrations were unrelated to either age or growth rate. Ninetieth centiles for fecal polyamines during the first week were 7668, 5176, 53, and 75 micromolar for cadaverine, putrescine, spermidine, and spermine, respectively. Conclusions: Fasting gastric fluid polyamine concentrations in premature infants are higher than those reported for either human milk or infant formulas. The high fecal cadaverine and putrescine concentrations are probably of bacterial origin. |
| doi_str_mv | 10.1097/00005176-199704000-00006 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79001412</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79001412</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5536-383772dae233c036872c99abf90a56e565902a4f30518c6e8eaa0b79b459967e3</originalsourceid><addsrcrecordid>eNp1UU1PGzEQtaoimtL-hAofqt4W_LFrr48IAa0E4kA5WxNnHFy83mDvCvHv65A0t_oympn3ZuY9E0I5O-PM6HNWX8e1argxmrU1a7Yl9YEseCdV0_aMfyQLJrRuBOfqE_lcyp-K0G3Hjsmx4W3LBVuQu2soU0hruq4xB0d9nMOKQlpRjw4i3YzxDYaQkLoxOUxThimMqdCQ6CbjANOcsSYe0lS-kCMPseDXfTwhj9dXvy9_Nrf3N78uL24b122vk73UWqwAhZSOSdVr4YyBpTcMOoWd6gwT0HpZNfZOYY8AbKnNsu2MURrlCfmxm7vJ48uMZbJDKA5jhITjXKw2jPEqsAL7HdDlsZSM3m5yGCC_Wc7s1kn7z0l7cPK9pCr1237HvBxwdSDurav97_s-lGqUz5BcKAeYqCKUlhXW7mCvY5wwl-c4v2K2TwhxerL_-8dKO93RPIwW1rlOfnwQjEsmeiVl3f8XZ2eTDg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79001412</pqid></control><display><type>article</type><title>Fasting gastric fluid and fecal polyamine concentrations in premature infants</title><source>Journals@Ovid Ovid Autoload</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Forget, P.P ; Degraeuwe, P.L.J ; Smeets, C ; Deutz, N.E.P</creator><creatorcontrib>Forget, P.P ; Degraeuwe, P.L.J ; Smeets, C ; Deutz, N.E.P</creatorcontrib><description>Background: The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid and fecal polyamine concentrations in premature infants during the postnatal period. We further compared gastric fluid polyamine concentrations with those reported for milk and looked for possible relationships between luminal polyamine concentrations, age, and growth rate. Methods: High-performance liquid chromatography was used for the measurement of polyamine concentrations in both fecal and gastric fluid samples. Results: Ninetieth centiles for gastric polyamines during the first week were 62, 28, 82, and 14 micromolar for putrescine, spermidine, spermine, and cadaverine, respectively. These values are higher than those reported for human milk and infant formulas. Polyamine concentrations were unrelated to either age or growth rate. Ninetieth centiles for fecal polyamines during the first week were 7668, 5176, 53, and 75 micromolar for cadaverine, putrescine, spermidine, and spermine, respectively. Conclusions: Fasting gastric fluid polyamine concentrations in premature infants are higher than those reported for either human milk or infant formulas. The high fecal cadaverine and putrescine concentrations are probably of bacterial origin.</description><identifier>ISSN: 0277-2116</identifier><identifier>EISSN: 1536-4801</identifier><identifier>DOI: 10.1097/00005176-199704000-00006</identifier><identifier>PMID: 9144120</identifier><identifier>CODEN: JPGND6</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott-Raven Publishers</publisher><subject>Aging ; Biological and medical sciences ; Cadaverine - analysis ; Chromatography, High Pressure Liquid ; Fasting ; Feces - chemistry ; Fundamental and applied biological sciences. Psychology ; Gastric Juice - chemistry ; Gestational Age ; human nutrition ; Humans ; Infant, Newborn ; Infant, Premature - metabolism ; nutrition physiology ; Polyamines - analysis ; Putrescine - analysis ; Reference Values ; Spermidine - analysis ; Spermine - analysis ; Stomach ; Vertebrates: digestive system</subject><ispartof>Journal of pediatric gastroenterology and nutrition, 1997-04, Vol.24 (4), p.389-392</ispartof><rights>Lippincott-Raven Publishers</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5536-383772dae233c036872c99abf90a56e565902a4f30518c6e8eaa0b79b459967e3</citedby><cites>FETCH-LOGICAL-c5536-383772dae233c036872c99abf90a56e565902a4f30518c6e8eaa0b79b459967e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,23909,23910,25118,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2659673$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9144120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Forget, P.P</creatorcontrib><creatorcontrib>Degraeuwe, P.L.J</creatorcontrib><creatorcontrib>Smeets, C</creatorcontrib><creatorcontrib>Deutz, N.E.P</creatorcontrib><title>Fasting gastric fluid and fecal polyamine concentrations in premature infants</title><title>Journal of pediatric gastroenterology and nutrition</title><addtitle>J Pediatr Gastroenterol Nutr</addtitle><description>Background: The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid and fecal polyamine concentrations in premature infants during the postnatal period. We further compared gastric fluid polyamine concentrations with those reported for milk and looked for possible relationships between luminal polyamine concentrations, age, and growth rate. Methods: High-performance liquid chromatography was used for the measurement of polyamine concentrations in both fecal and gastric fluid samples. Results: Ninetieth centiles for gastric polyamines during the first week were 62, 28, 82, and 14 micromolar for putrescine, spermidine, spermine, and cadaverine, respectively. These values are higher than those reported for human milk and infant formulas. Polyamine concentrations were unrelated to either age or growth rate. Ninetieth centiles for fecal polyamines during the first week were 7668, 5176, 53, and 75 micromolar for cadaverine, putrescine, spermidine, and spermine, respectively. Conclusions: Fasting gastric fluid polyamine concentrations in premature infants are higher than those reported for either human milk or infant formulas. The high fecal cadaverine and putrescine concentrations are probably of bacterial origin.</description><subject>Aging</subject><subject>Biological and medical sciences</subject><subject>Cadaverine - analysis</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Fasting</subject><subject>Feces - chemistry</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gastric Juice - chemistry</subject><subject>Gestational Age</subject><subject>human nutrition</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature - metabolism</subject><subject>nutrition physiology</subject><subject>Polyamines - analysis</subject><subject>Putrescine - analysis</subject><subject>Reference Values</subject><subject>Spermidine - analysis</subject><subject>Spermine - analysis</subject><subject>Stomach</subject><subject>Vertebrates: digestive system</subject><issn>0277-2116</issn><issn>1536-4801</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UU1PGzEQtaoimtL-hAofqt4W_LFrr48IAa0E4kA5WxNnHFy83mDvCvHv65A0t_oympn3ZuY9E0I5O-PM6HNWX8e1argxmrU1a7Yl9YEseCdV0_aMfyQLJrRuBOfqE_lcyp-K0G3Hjsmx4W3LBVuQu2soU0hruq4xB0d9nMOKQlpRjw4i3YzxDYaQkLoxOUxThimMqdCQ6CbjANOcsSYe0lS-kCMPseDXfTwhj9dXvy9_Nrf3N78uL24b122vk73UWqwAhZSOSdVr4YyBpTcMOoWd6gwT0HpZNfZOYY8AbKnNsu2MURrlCfmxm7vJ48uMZbJDKA5jhITjXKw2jPEqsAL7HdDlsZSM3m5yGCC_Wc7s1kn7z0l7cPK9pCr1237HvBxwdSDurav97_s-lGqUz5BcKAeYqCKUlhXW7mCvY5wwl-c4v2K2TwhxerL_-8dKO93RPIwW1rlOfnwQjEsmeiVl3f8XZ2eTDg</recordid><startdate>199704</startdate><enddate>199704</enddate><creator>Forget, P.P</creator><creator>Degraeuwe, P.L.J</creator><creator>Smeets, C</creator><creator>Deutz, N.E.P</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199704</creationdate><title>Fasting gastric fluid and fecal polyamine concentrations in premature infants</title><author>Forget, P.P ; Degraeuwe, P.L.J ; Smeets, C ; Deutz, N.E.P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5536-383772dae233c036872c99abf90a56e565902a4f30518c6e8eaa0b79b459967e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Aging</topic><topic>Biological and medical sciences</topic><topic>Cadaverine - analysis</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Fasting</topic><topic>Feces - chemistry</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gastric Juice - chemistry</topic><topic>Gestational Age</topic><topic>human nutrition</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature - metabolism</topic><topic>nutrition physiology</topic><topic>Polyamines - analysis</topic><topic>Putrescine - analysis</topic><topic>Reference Values</topic><topic>Spermidine - analysis</topic><topic>Spermine - analysis</topic><topic>Stomach</topic><topic>Vertebrates: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Forget, P.P</creatorcontrib><creatorcontrib>Degraeuwe, P.L.J</creatorcontrib><creatorcontrib>Smeets, C</creatorcontrib><creatorcontrib>Deutz, N.E.P</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric gastroenterology and nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Forget, P.P</au><au>Degraeuwe, P.L.J</au><au>Smeets, C</au><au>Deutz, N.E.P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fasting gastric fluid and fecal polyamine concentrations in premature infants</atitle><jtitle>Journal of pediatric gastroenterology and nutrition</jtitle><addtitle>J Pediatr Gastroenterol Nutr</addtitle><date>1997-04</date><risdate>1997</risdate><volume>24</volume><issue>4</issue><spage>389</spage><epage>392</epage><pages>389-392</pages><issn>0277-2116</issn><eissn>1536-4801</eissn><coden>JPGND6</coden><abstract>Background: The role of milk polyamines in the development of the gastrointestinal tract of human infants is presently unknown. Polyamine concentrations are higher in human milk than in infant formulas. The aim of the present study was to gather data on luminal polyamines by measuring gastric fluid and fecal polyamine concentrations in premature infants during the postnatal period. We further compared gastric fluid polyamine concentrations with those reported for milk and looked for possible relationships between luminal polyamine concentrations, age, and growth rate. Methods: High-performance liquid chromatography was used for the measurement of polyamine concentrations in both fecal and gastric fluid samples. Results: Ninetieth centiles for gastric polyamines during the first week were 62, 28, 82, and 14 micromolar for putrescine, spermidine, spermine, and cadaverine, respectively. These values are higher than those reported for human milk and infant formulas. Polyamine concentrations were unrelated to either age or growth rate. Ninetieth centiles for fecal polyamines during the first week were 7668, 5176, 53, and 75 micromolar for cadaverine, putrescine, spermidine, and spermine, respectively. Conclusions: Fasting gastric fluid polyamine concentrations in premature infants are higher than those reported for either human milk or infant formulas. The high fecal cadaverine and putrescine concentrations are probably of bacterial origin.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>9144120</pmid><doi>10.1097/00005176-199704000-00006</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0277-2116 |
| ispartof | Journal of pediatric gastroenterology and nutrition, 1997-04, Vol.24 (4), p.389-392 |
| issn | 0277-2116 1536-4801 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79001412 |
| source | Journals@Ovid Ovid Autoload; MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aging Biological and medical sciences Cadaverine - analysis Chromatography, High Pressure Liquid Fasting Feces - chemistry Fundamental and applied biological sciences. Psychology Gastric Juice - chemistry Gestational Age human nutrition Humans Infant, Newborn Infant, Premature - metabolism nutrition physiology Polyamines - analysis Putrescine - analysis Reference Values Spermidine - analysis Spermine - analysis Stomach Vertebrates: digestive system |
| title | Fasting gastric fluid and fecal polyamine concentrations in premature infants |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T18%3A41%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fasting%20gastric%20fluid%20and%20fecal%20polyamine%20concentrations%20in%20premature%20infants&rft.jtitle=Journal%20of%20pediatric%20gastroenterology%20and%20nutrition&rft.au=Forget,%20P.P&rft.date=1997-04&rft.volume=24&rft.issue=4&rft.spage=389&rft.epage=392&rft.pages=389-392&rft.issn=0277-2116&rft.eissn=1536-4801&rft.coden=JPGND6&rft_id=info:doi/10.1097/00005176-199704000-00006&rft_dat=%3Cproquest_cross%3E79001412%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79001412&rft_id=info:pmid/9144120&rfr_iscdi=true |