Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines

In the hemopoietic system c-myb expression is required for proliferation of immature cells and its down-regulation is required for differentiation. In colonic mucosa c-myb expression occurs at levels comparable to immature hemopoietic cells. Inhibition of c-myb expression in colon cell lines, using...

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