Amino Acid Variants in the Human Leptin Receptor: Lack of Association to Juvenile Onset Obesity

The recently described putative lipostat system mediated in part by leptin and its hypothalamic receptor provides logical candidate genes for the molecular basis of inherited obesity in humans on the basis of the occurrence of profound obesity observed in obese and diabetic mice, in which the genes...

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Veröffentlicht in:	Biochemical and biophysical research communications 1997-04, Vol.233 (1), p.248-252
Hauptverfasser:	Echwald, Søren M., Sørensen, Tina D., Sørensen, Thorkild I.A., Tybjærg-Hansen, Anne, Andersen, Teis, Chung, Wendy K., Leibel, Rudolph L., Pedersen, Oluf
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Amino Acids - genetics Carrier Proteins - genetics Child Humans Middle Aged Mutation Obesity - genetics Polymorphism, Single-Stranded Conformational Receptors, Cell Surface Receptors, Cytokine - genetics Receptors, Leptin
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