Fatal Streptobacillus moniliformis infection in a two-month-old infant

Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This...

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Veröffentlicht in:American journal of clinical pathology 1989-05, Vol.91 (5), p.612-616
Hauptverfasser: SENS, M. A, BROWN, E. W, WILSON, L. R, CROCKER, T. P
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container_title American journal of clinical pathology
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creator SENS, M. A
BROWN, E. W
WILSON, L. R
CROCKER, T. P
description Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This report describes a fatal case of Streptobacillus moniliformis in an infant bitten by a wild rat. The autopsy findings included an interstitial pneumonia, fibrinous endocarditis, mild mononuclear meningitis, hepatosplenomegaly and lymphadenopathy, erythrophagocytosis, and sinusoidal mononuclear cell infiltrates in regional lymph nodes and the liver. To the authors' knowledge, this is the first report of the autopsy pathology findings of this agent.
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subjects Autopsy
Bacterial diseases
Bacterial Infections - mortality
Biological and medical sciences
Human bacterial diseases
Humans
Infant
Infectious diseases
Male
Medical sciences
Miscellaneous
Pulmonary Fibrosis - etiology
Pulmonary Fibrosis - pathology
Rat-Bite Fever - complications
Streptobacillus
title Fatal Streptobacillus moniliformis infection in a two-month-old infant
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