Fatal Streptobacillus moniliformis infection in a two-month-old infant
Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This...
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Veröffentlicht in: | American journal of clinical pathology 1989-05, Vol.91 (5), p.612-616 |
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container_title | American journal of clinical pathology |
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creator | SENS, M. A BROWN, E. W WILSON, L. R CROCKER, T. P |
description | Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This report describes a fatal case of Streptobacillus moniliformis in an infant bitten by a wild rat. The autopsy findings included an interstitial pneumonia, fibrinous endocarditis, mild mononuclear meningitis, hepatosplenomegaly and lymphadenopathy, erythrophagocytosis, and sinusoidal mononuclear cell infiltrates in regional lymph nodes and the liver. To the authors' knowledge, this is the first report of the autopsy pathology findings of this agent. |
doi_str_mv | 10.1093/ajcp/91.5.612 |
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A</creatorcontrib><creatorcontrib>BROWN, E. W</creatorcontrib><creatorcontrib>WILSON, L. R</creatorcontrib><creatorcontrib>CROCKER, T. P</creatorcontrib><title>Fatal Streptobacillus moniliformis infection in a two-month-old infant</title><title>American journal of clinical pathology</title><addtitle>Am J Clin Pathol</addtitle><description>Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This report describes a fatal case of Streptobacillus moniliformis in an infant bitten by a wild rat. The autopsy findings included an interstitial pneumonia, fibrinous endocarditis, mild mononuclear meningitis, hepatosplenomegaly and lymphadenopathy, erythrophagocytosis, and sinusoidal mononuclear cell infiltrates in regional lymph nodes and the liver. To the authors' knowledge, this is the first report of the autopsy pathology findings of this agent.</description><subject>Autopsy</subject><subject>Bacterial diseases</subject><subject>Bacterial Infections - mortality</subject><subject>Biological and medical sciences</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Pulmonary Fibrosis - etiology</subject><subject>Pulmonary Fibrosis - pathology</subject><subject>Rat-Bite Fever - complications</subject><subject>Streptobacillus</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLAzEURoMotVaXLoVZiLtp85i8llKsCgUX6jpkMhlMyUzGJEX8907p0K2re-EcPi7fBeAWwSWCkqz0zgwriZZ0yRA-A3MkK1JyjvE5mEMIcSkRJ5fgKqUdhAgLWM3ADHMkJMNzsNnorH3xnqMdcqi1cd7vU9GF3nnXhti5VLi-tSa70I9boYv8E8qR568y-OYAdZ-vwUWrfbI301yAz83Tx_ql3L49v64ft6UhEOOysowIKrHQvOaCG8Gw4YYYgpGpTMOoRZByS-q6rnTFLa-wILZtGmJaSDEmC_BwzB1i-N7blNV4oLHe696GfVJcSMkEZP-KiBKKGCGjWB5FE0NK0bZqiK7T8VchqA4Fq0PBSiJF1Vjw6N9Nwfu6s83Jnhod-f3EdTLat1H3xqWTxjEdH8TIHyCkgxE</recordid><startdate>198905</startdate><enddate>198905</enddate><creator>SENS, M. A</creator><creator>BROWN, E. W</creator><creator>WILSON, L. R</creator><creator>CROCKER, T. P</creator><general>American Society of Clinical Pathologists</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>198905</creationdate><title>Fatal Streptobacillus moniliformis infection in a two-month-old infant</title><author>SENS, M. A ; BROWN, E. W ; WILSON, L. R ; CROCKER, T. 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P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatal Streptobacillus moniliformis infection in a two-month-old infant</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>1989-05</date><risdate>1989</risdate><volume>91</volume><issue>5</issue><spage>612</spage><epage>616</epage><pages>612-616</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><coden>AJCPAI</coden><abstract>Streptobacillus moniliformis is an uncommon human pathogen contracted from exposure to rodents. It usually produces a mild, protracted illness (rat-bite fever, Haverhill fever, erythema arthriticum epidemicum) that has either a favorable response to antibiotic therapy or spontaneously resolves. This report describes a fatal case of Streptobacillus moniliformis in an infant bitten by a wild rat. The autopsy findings included an interstitial pneumonia, fibrinous endocarditis, mild mononuclear meningitis, hepatosplenomegaly and lymphadenopathy, erythrophagocytosis, and sinusoidal mononuclear cell infiltrates in regional lymph nodes and the liver. To the authors' knowledge, this is the first report of the autopsy pathology findings of this agent.</abstract><cop>Chicago, IL</cop><pub>American Society of Clinical Pathologists</pub><pmid>2718962</pmid><doi>10.1093/ajcp/91.5.612</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Autopsy Bacterial diseases Bacterial Infections - mortality Biological and medical sciences Human bacterial diseases Humans Infant Infectious diseases Male Medical sciences Miscellaneous Pulmonary Fibrosis - etiology Pulmonary Fibrosis - pathology Rat-Bite Fever - complications Streptobacillus |
title | Fatal Streptobacillus moniliformis infection in a two-month-old infant |
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