Bacterial metabolites sodium butyrate and propionate inhibit epithelial cell growth in vitro

The structural and functional barrier preventing the free advancement of microbial plaque subgingivally along the tooth surface is formed by the junctional epithelial (JE) cells directly attached to the tooth (DAT cells). The mechanism leading to degeneration of the DAT cells is not known. In the pr...

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Veröffentlicht in:	Journal of periodontal research 1997-04, Vol.32 (3), p.326-334
Hauptverfasser:	Pöllänen, M. T., Overman, D. O., Salonen, J. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Bacteria - chemistry Bacteria - metabolism Biological and medical sciences Butyrates - pharmacology Butyric Acid Cell Adhesion - drug effects Cell Division - drug effects Cell Line Culture Techniques Cytoplasm - drug effects Cytoplasm - ultrastructure Dental Plaque - chemistry Dentistry Dose-Response Relationship, Drug epithelial attachment Epithelial Attachment - cytology Epithelial Attachment - drug effects Facial bones, jaws, teeth, parodontium: diseases, semeiology Gingival Crevicular Fluid - chemistry growth Humans Intermediate Filaments - drug effects junctional epithelium Medical sciences Microscopy, Electron Non tumoral diseases Otorhinolaryngology. Stomatology periodontal pathology Propionates - pharmacology short chain fatty acids Swine Vacuoles
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