Hemodynamic effects of fructose 1,6-diphosphate in patients with normal and impaired left ventricular function

Hemodynamic effects of fructose 1,6-diphosphate in patients with normal and impaired left ventricular function

We compared the short-term hemodynamic effects of intravenous fructose 1,6-diphosphate (FDP) administration in patients with coronary artery disease. Hemodynamic measurements were performed before and after administration of FDP in two groups of patients: those with impaired left ventricular (LV) fu...

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Veröffentlicht in:The American heart journal 1997-05, Vol.133 (5), p.541-549
Hauptverfasser: Markov, Angel K., Brumley, Michael A., Figueroa, Alfredo, Skelton, Thomas N., Lehan, Patrick H.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cardiac Catheterization
Cardiotonic agents
Cardiovascular system
Case-Control Studies
Coronary Disease - physiopathology
Energy Metabolism - drug effects
Female
Fructosediphosphates - administration & dosage
Fructosediphosphates - pharmacology
Hemodynamics - drug effects
Humans
Infusions, Intravenous
Male
Medical sciences
Middle Aged
Myocardium - metabolism
Pharmacology. Drug treatments
Time Factors
Ventricular Dysfunction, Left - physiopathology
Ventricular Function, Left - drug effects
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Zusammenfassung:We compared the short-term hemodynamic effects of intravenous fructose 1,6-diphosphate (FDP) administration in patients with coronary artery disease. Hemodynamic measurements were performed before and after administration of FDP in two groups of patients: those with impaired left ventricular (LV) function, elevated LV end-diastolic pressures (LVEDP ≥12 mm Hg, n = 30), and those with normal LV function (LVEDP
ISSN:0002-8703
1097-6744
DOI:10.1016/S0002-8703(97)70149-2