Pentoxifylline in treatment of sarcoidosis

The optimal therapy for sarcoidosis remains unclear. Most patients show a short-term response to corticosteroid therapy, but they have to face the risk of significant side effects. Because tumor necrosis factor alpha (TNF) plays a critical role in granuloma formation and sustenance as well as in the...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1997-05, Vol.155 (5), p.1665-1669
Hauptverfasser:	ZABEL, P, ENTZIAN, P, DALHOFF, K, SCHLAAK, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Drug Therapy, Combination Female Glucocorticoids - administration & dosage Humans Male Medical sciences Miscellaneous Pentoxifylline - administration & dosage Pentoxifylline - therapeutic use Pharmacology. Drug treatments Phosphodiesterase Inhibitors - therapeutic use Prednisone - administration & dosage Pulmonary Gas Exchange Respiratory Mechanics Sarcoidosis, Pulmonary - drug therapy Sarcoidosis, Pulmonary - physiopathology Tumor Necrosis Factor-alpha - metabolism
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