Splenectomy for massive splenomegaly
Twenty‐four patients who underwent resection of giant spleen (spleen weight > 1·5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Althou...
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| Veröffentlicht in: | British journal of surgery 1989-04, Vol.76 (4), p.395-397 |
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| container_title | British journal of surgery |
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| creator | Shaw, J. H. F. Clark, M. |
| description | Twenty‐four patients who underwent resection of giant spleen (spleen weight > 1·5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Although morbidity was higher in patients with giant spleens compared with those undergoing resection of smaller spleens the incidence of serious complications was small, and there were no operative or in‐hospital deaths. In addition, virtually all patients benefited either on the basis of minimized haematological defect, or palliation of symtoms. Further, the injection of 1 ml of 1:10000 adrenaline into the splenic artery before splenic mobilization reduced the splenic volume by approximately 40 per cent on average, and resulted in improved exposure, thereby facilitating the procedure. |
| doi_str_mv | 10.1002/bjs.1800760426 |
| format | Article |
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H. F. ; Clark, M.</creator><creatorcontrib>Shaw, J. H. F. ; Clark, M.</creatorcontrib><description>Twenty‐four patients who underwent resection of giant spleen (spleen weight > 1·5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Although morbidity was higher in patients with giant spleens compared with those undergoing resection of smaller spleens the incidence of serious complications was small, and there were no operative or in‐hospital deaths. In addition, virtually all patients benefited either on the basis of minimized haematological defect, or palliation of symtoms. Further, the injection of 1 ml of 1:10000 adrenaline into the splenic artery before splenic mobilization reduced the splenic volume by approximately 40 per cent on average, and resulted in improved exposure, thereby facilitating the procedure.</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.1800760426</identifier><identifier>PMID: 2720352</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Bristol: John Wiley & Sons, Ltd</publisher><subject>adrenaline ; Aged ; Biological and medical sciences ; Blood Pressure - drug effects ; Elective splenectomy ; Epinephrine - therapeutic use ; Female ; giant spleen ; haematological disorders ; Heart Rate - drug effects ; Hematologic and hematopoietic diseases ; Hodgkin's lymphoma ; Humans ; Intraoperative Care - methods ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Male ; Medical sciences ; Middle Aged ; overwhelming infections ; Postoperative Complications ; Spleen - pathology ; Splenectomy - methods ; Splenomegaly - etiology ; Splenomegaly - surgery ; thrombocytopenia</subject><ispartof>British journal of surgery, 1989-04, Vol.76 (4), p.395-397</ispartof><rights>Copyright © 1989 British Journal of Surgery Society Ltd.</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3686-81cfeeaa376556f57b0b98dc68cb1a3dd068a9949e1807c2c92fae936c03fc113</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.1800760426$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.1800760426$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7181029$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2720352$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shaw, J. H. F.</creatorcontrib><creatorcontrib>Clark, M.</creatorcontrib><title>Splenectomy for massive splenomegaly</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Twenty‐four patients who underwent resection of giant spleen (spleen weight > 1·5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Although morbidity was higher in patients with giant spleens compared with those undergoing resection of smaller spleens the incidence of serious complications was small, and there were no operative or in‐hospital deaths. In addition, virtually all patients benefited either on the basis of minimized haematological defect, or palliation of symtoms. Further, the injection of 1 ml of 1:10000 adrenaline into the splenic artery before splenic mobilization reduced the splenic volume by approximately 40 per cent on average, and resulted in improved exposure, thereby facilitating the procedure.</description><subject>adrenaline</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure - drug effects</subject><subject>Elective splenectomy</subject><subject>Epinephrine - therapeutic use</subject><subject>Female</subject><subject>giant spleen</subject><subject>haematological disorders</subject><subject>Heart Rate - drug effects</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hodgkin's lymphoma</subject><subject>Humans</subject><subject>Intraoperative Care - methods</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>overwhelming infections</subject><subject>Postoperative Complications</subject><subject>Spleen - pathology</subject><subject>Splenectomy - methods</subject><subject>Splenomegaly - etiology</subject><subject>Splenomegaly - surgery</subject><subject>thrombocytopenia</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1PwkAQxTdGg4hevZlwIN6Ks7t0P45KFFSCiWg8brbbqSm2FLtU7X9vCQ2cJjPv9yYzj5BLCkMKwG6ipR9SBSAFjJg4Il3KRRgwKtQx6UIzDyhn_JSceb8EoBxC1iEdJhnwkHXJYLHOcIVuU-R1PynKfm69T3-w77fzIsdPm9Xn5CSxmceLtvbI-8P923gazF4mj-PbWeC4UCJQ1CWI1nIpwlAkoYwg0ip2QrmIWh7HIJTVeqSxOVg65jRLLGouHPDEUcp75Hq3d10W3xX6jclT7zDL7AqLyhuptNIcoAGvWrCKcozNukxzW9amfavRB61uvbNZUtqVS_0ek1RRYLrB9A77TTOs9zIFs43WNNGaQ7Tm7mlx6BpvsPOmfoN_e68tv4yQXIbmYz4xegqT2evzwsz5P3L0en8</recordid><startdate>198904</startdate><enddate>198904</enddate><creator>Shaw, J. H. F.</creator><creator>Clark, M.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198904</creationdate><title>Splenectomy for massive splenomegaly</title><author>Shaw, J. H. F. ; Clark, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3686-81cfeeaa376556f57b0b98dc68cb1a3dd068a9949e1807c2c92fae936c03fc113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>adrenaline</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - drug effects</topic><topic>Elective splenectomy</topic><topic>Epinephrine - therapeutic use</topic><topic>Female</topic><topic>giant spleen</topic><topic>haematological disorders</topic><topic>Heart Rate - drug effects</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hodgkin's lymphoma</topic><topic>Humans</topic><topic>Intraoperative Care - methods</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>overwhelming infections</topic><topic>Postoperative Complications</topic><topic>Spleen - pathology</topic><topic>Splenectomy - methods</topic><topic>Splenomegaly - etiology</topic><topic>Splenomegaly - surgery</topic><topic>thrombocytopenia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shaw, J. H. F.</creatorcontrib><creatorcontrib>Clark, M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shaw, J. H. F.</au><au>Clark, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Splenectomy for massive splenomegaly</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>1989-04</date><risdate>1989</risdate><volume>76</volume><issue>4</issue><spage>395</spage><epage>397</epage><pages>395-397</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Twenty‐four patients who underwent resection of giant spleen (spleen weight > 1·5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Although morbidity was higher in patients with giant spleens compared with those undergoing resection of smaller spleens the incidence of serious complications was small, and there were no operative or in‐hospital deaths. In addition, virtually all patients benefited either on the basis of minimized haematological defect, or palliation of symtoms. Further, the injection of 1 ml of 1:10000 adrenaline into the splenic artery before splenic mobilization reduced the splenic volume by approximately 40 per cent on average, and resulted in improved exposure, thereby facilitating the procedure.</abstract><cop>Bristol</cop><pub>John Wiley & Sons, Ltd</pub><pmid>2720352</pmid><doi>10.1002/bjs.1800760426</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | British journal of surgery, 1989-04, Vol.76 (4), p.395-397 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | adrenaline Aged Biological and medical sciences Blood Pressure - drug effects Elective splenectomy Epinephrine - therapeutic use Female giant spleen haematological disorders Heart Rate - drug effects Hematologic and hematopoietic diseases Hodgkin's lymphoma Humans Intraoperative Care - methods Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged overwhelming infections Postoperative Complications Spleen - pathology Splenectomy - methods Splenomegaly - etiology Splenomegaly - surgery thrombocytopenia |
| title | Splenectomy for massive splenomegaly |
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