Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex
: Plasma osmolality and the levels of water, taurine, and total amino nitrogen (detected as ninhydrin‐positive substances) have been measured in the cerebral cortices of nonpregnant and 19‐day pregnant Wistar rats. Plasma osmolality fell by 11 mosmol/kg during pregnancy. Brain water content remained...
Gespeichert in:
| Veröffentlicht in: | Journal of neurochemistry 1989-07, Vol.53 (1), p.300-302 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 302 |
|---|---|
| container_issue | 1 |
| container_start_page | 300 |
| container_title | Journal of neurochemistry |
| container_volume | 53 |
| creator | Law, R. O. |
| description | : Plasma osmolality and the levels of water, taurine, and total amino nitrogen (detected as ninhydrin‐positive substances) have been measured in the cerebral cortices of nonpregnant and 19‐day pregnant Wistar rats. Plasma osmolality fell by 11 mosmol/kg during pregnancy. Brain water content remained unaltered, but levels of taurine and ninhydrin‐positive substances fell by 48.5 and 21.9%, respectively. It is suggested that one way in which brain cells are prevented from swelling during the mild hypoosmolality of pregnancy is through loss of cellular amino nitrogen, particularly taurine. |
| doi_str_mv | 10.1111/j.1471-4159.1989.tb07328.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78989191</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78989191</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4000-2b01e58f417a2effd6e3020ac96fa7c05948caae5e6f808c6230a3db2c9730cc3</originalsourceid><addsrcrecordid>eNqVkc1LKzEUxYM88dXqnyAEF2_ljDfJfLp4IIOfiIpUXIZMetM3ZZpokmL73zulxe3Du7mL37nnwjmEnDJI2TDn85RlJUsyltcpq6s6jS2Uglfpao-MvtEvMgLgPBGQ8d_kMIQ5ACuygh2QA15yURQwIrMrY1DHQJ2hzx5nVlm9ps7S-A9p42xEu4VvKqI_oxO19J3FM6rslE5cVD29XHTW0ccuejdDSztLX1SkDXps_YAb5yOujsi-UX3A490ek9frq0lzmzw83dw1lw-JzgAg4S0wzCuTsVJxNGZaoAAOSteFUaWGvM4qrRTmWJgKKl1wAUpMW67rUoDWYkz-bH3fvftYYohy0QWNfa8sumWQZTXkxWr2XyHLBQg2uI7JxVaovQvBo5Hvvlsov5YM5KYOOZebzOUmc7mpQ-7qkKvh-GT3ZdkucPp9ust_4H-3_LPrcf0DZ3n_2AgA8QXQLJne</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15303197</pqid></control><display><type>article</type><title>Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Law, R. O.</creator><creatorcontrib>Law, R. O.</creatorcontrib><description>: Plasma osmolality and the levels of water, taurine, and total amino nitrogen (detected as ninhydrin‐positive substances) have been measured in the cerebral cortices of nonpregnant and 19‐day pregnant Wistar rats. Plasma osmolality fell by 11 mosmol/kg during pregnancy. Brain water content remained unaltered, but levels of taurine and ninhydrin‐positive substances fell by 48.5 and 21.9%, respectively. It is suggested that one way in which brain cells are prevented from swelling during the mild hypoosmolality of pregnancy is through loss of cellular amino nitrogen, particularly taurine.</description><identifier>ISSN: 0022-3042</identifier><identifier>EISSN: 1471-4159</identifier><identifier>DOI: 10.1111/j.1471-4159.1989.tb07328.x</identifier><identifier>PMID: 2723660</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Amino nitrogen ; Animals ; Body Water - metabolism ; Brain cells ; Cell volume ; Cerebral Cortex - metabolism ; Female ; Ninhydrin ; Nitrogen - metabolism ; Osmolar Concentration ; Pregnancy ; Pregnancy, Animal - blood ; Pregnancy, Animal - metabolism ; Rats ; Rats, Inbred Strains ; Taurine ; Taurine - metabolism</subject><ispartof>Journal of neurochemistry, 1989-07, Vol.53 (1), p.300-302</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4000-2b01e58f417a2effd6e3020ac96fa7c05948caae5e6f808c6230a3db2c9730cc3</citedby><cites>FETCH-LOGICAL-c4000-2b01e58f417a2effd6e3020ac96fa7c05948caae5e6f808c6230a3db2c9730cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1471-4159.1989.tb07328.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1471-4159.1989.tb07328.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2723660$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Law, R. O.</creatorcontrib><title>Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex</title><title>Journal of neurochemistry</title><addtitle>J Neurochem</addtitle><description>: Plasma osmolality and the levels of water, taurine, and total amino nitrogen (detected as ninhydrin‐positive substances) have been measured in the cerebral cortices of nonpregnant and 19‐day pregnant Wistar rats. Plasma osmolality fell by 11 mosmol/kg during pregnancy. Brain water content remained unaltered, but levels of taurine and ninhydrin‐positive substances fell by 48.5 and 21.9%, respectively. It is suggested that one way in which brain cells are prevented from swelling during the mild hypoosmolality of pregnancy is through loss of cellular amino nitrogen, particularly taurine.</description><subject>Amino nitrogen</subject><subject>Animals</subject><subject>Body Water - metabolism</subject><subject>Brain cells</subject><subject>Cell volume</subject><subject>Cerebral Cortex - metabolism</subject><subject>Female</subject><subject>Ninhydrin</subject><subject>Nitrogen - metabolism</subject><subject>Osmolar Concentration</subject><subject>Pregnancy</subject><subject>Pregnancy, Animal - blood</subject><subject>Pregnancy, Animal - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Taurine</subject><subject>Taurine - metabolism</subject><issn>0022-3042</issn><issn>1471-4159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkc1LKzEUxYM88dXqnyAEF2_ljDfJfLp4IIOfiIpUXIZMetM3ZZpokmL73zulxe3Du7mL37nnwjmEnDJI2TDn85RlJUsyltcpq6s6jS2Uglfpao-MvtEvMgLgPBGQ8d_kMIQ5ACuygh2QA15yURQwIrMrY1DHQJ2hzx5nVlm9ps7S-A9p42xEu4VvKqI_oxO19J3FM6rslE5cVD29XHTW0ccuejdDSztLX1SkDXps_YAb5yOujsi-UX3A490ek9frq0lzmzw83dw1lw-JzgAg4S0wzCuTsVJxNGZaoAAOSteFUaWGvM4qrRTmWJgKKl1wAUpMW67rUoDWYkz-bH3fvftYYohy0QWNfa8sumWQZTXkxWr2XyHLBQg2uI7JxVaovQvBo5Hvvlsov5YM5KYOOZebzOUmc7mpQ-7qkKvh-GT3ZdkucPp9ust_4H-3_LPrcf0DZ3n_2AgA8QXQLJne</recordid><startdate>198907</startdate><enddate>198907</enddate><creator>Law, R. O.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>198907</creationdate><title>Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex</title><author>Law, R. O.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4000-2b01e58f417a2effd6e3020ac96fa7c05948caae5e6f808c6230a3db2c9730cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Amino nitrogen</topic><topic>Animals</topic><topic>Body Water - metabolism</topic><topic>Brain cells</topic><topic>Cell volume</topic><topic>Cerebral Cortex - metabolism</topic><topic>Female</topic><topic>Ninhydrin</topic><topic>Nitrogen - metabolism</topic><topic>Osmolar Concentration</topic><topic>Pregnancy</topic><topic>Pregnancy, Animal - blood</topic><topic>Pregnancy, Animal - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Taurine</topic><topic>Taurine - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Law, R. O.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of neurochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Law, R. O.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex</atitle><jtitle>Journal of neurochemistry</jtitle><addtitle>J Neurochem</addtitle><date>1989-07</date><risdate>1989</risdate><volume>53</volume><issue>1</issue><spage>300</spage><epage>302</epage><pages>300-302</pages><issn>0022-3042</issn><eissn>1471-4159</eissn><abstract>: Plasma osmolality and the levels of water, taurine, and total amino nitrogen (detected as ninhydrin‐positive substances) have been measured in the cerebral cortices of nonpregnant and 19‐day pregnant Wistar rats. Plasma osmolality fell by 11 mosmol/kg during pregnancy. Brain water content remained unaltered, but levels of taurine and ninhydrin‐positive substances fell by 48.5 and 21.9%, respectively. It is suggested that one way in which brain cells are prevented from swelling during the mild hypoosmolality of pregnancy is through loss of cellular amino nitrogen, particularly taurine.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2723660</pmid><doi>10.1111/j.1471-4159.1989.tb07328.x</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3042 |
| ispartof | Journal of neurochemistry, 1989-07, Vol.53 (1), p.300-302 |
| issn | 0022-3042 1471-4159 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78989191 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Amino nitrogen Animals Body Water - metabolism Brain cells Cell volume Cerebral Cortex - metabolism Female Ninhydrin Nitrogen - metabolism Osmolar Concentration Pregnancy Pregnancy, Animal - blood Pregnancy, Animal - metabolism Rats Rats, Inbred Strains Taurine Taurine - metabolism |
| title | Effects of Pregnancy on the Contents of Water, Taurine, and Total Amino Nitrogen in Rat Cerebral Cortex |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T02%3A47%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20Pregnancy%20on%20the%20Contents%20of%20Water,%20Taurine,%20and%20Total%20Amino%20Nitrogen%20in%20Rat%20Cerebral%20Cortex&rft.jtitle=Journal%20of%20neurochemistry&rft.au=Law,%20R.%20O.&rft.date=1989-07&rft.volume=53&rft.issue=1&rft.spage=300&rft.epage=302&rft.pages=300-302&rft.issn=0022-3042&rft.eissn=1471-4159&rft_id=info:doi/10.1111/j.1471-4159.1989.tb07328.x&rft_dat=%3Cproquest_cross%3E78989191%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15303197&rft_id=info:pmid/2723660&rfr_iscdi=true |