Experimental autoimmune uveitis in HLA-B27 transgenic mice

The major histocompatibility complex (MHC) gene, HLA-B27 is strongly associated with autoimmune uveitis and spondyloarthropathies in humans. Experimental mouse models of autoimmune uveitis involve systemic immunization with the retinal autoantigen interphotoreceptor retinoid binding protein (IRBP)....

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Veröffentlicht in:	Human immunology 1997-04, Vol.53 (2), p.188-194
Hauptverfasser:	Willbanks, G.A., Rootman, D.S., Jay, V., Wiggert, B., Chamberlain, J., Inman, R.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune Diseases - etiology Autoimmune Diseases - genetics Autoimmune Diseases - pathology Eye Proteins - administration & dosage Eye Proteins - immunology Female HLA-A2 Antigen - genetics HLA-B27 Antigen - genetics Humans Injections, Subcutaneous Male Mice Mice, Inbred C57BL Mice, Transgenic Retinol-Binding Proteins - administration & dosage Retinol-Binding Proteins - immunology Transgenes - immunology Uveitis - etiology Uveitis - genetics
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