Restricted use of cationic germline V(H) gene segments in human Rh(D) red cell antibodies

The human red cell Rh(D) antigen elicits the production of high-affinity IgG antibodies, which can prevent blood transfusion and cause hemolytic disease of the newborn. It has been known for 20 years that Rh(D) antibodies are among the most positively charged human serum IgGs. Analysis by IEF of 9 h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 1997-05, Vol.89 (9), p.3277-3286
Hauptverfasser:	Boucher, G, Broly, H, Lemieux, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - isolation & purification Base Sequence Cloning, Molecular Consensus Sequence Erythrocytes - immunology Genes, Immunoglobulin Humans Hybridomas Immunoglobulin G - biosynthesis Immunoglobulin G - genetics Immunoglobulin G - isolation & purification Immunoglobulin Heavy Chains - biosynthesis Immunoglobulin Heavy Chains - genetics Immunoglobulin Heavy Chains - isolation & purification Immunoglobulin Isotypes - chemistry Immunoglobulin Isotypes - genetics Immunoglobulin kappa-Chains - genetics Immunoglobulin kappa-Chains - isolation & purification Immunoglobulin Variable Region - biosynthesis Immunoglobulin Variable Region - genetics Immunoglobulin Variable Region - isolation & purification Infant, Newborn Isoelectric Focusing Mice Molecular Sequence Data Polymerase Chain Reaction Recombinant Proteins - biosynthesis Recombinant Proteins - isolation & purification Rh-Hr Blood-Group System - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!