An Extracellular Domain of the Insulin Receptor β-Subunit with Regulatory Function on Protein-Tyrosine Kinase

Anti-insulin receptor monoclonal antibody MA-10 inhibits insulin receptor autophosphorylation of purified rat liver insulin receptors without affecting insulin binding (Cordera, R., Andraghetti, G., Gherzi, R., Adezati, L., Montemurro, A., Lauro, R., Goldfine, I. D., and De Pirro, R. (1987) Endocrin...

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Veröffentlicht in:	The Journal of biological chemistry 1989-05, Vol.264 (15), p.8627-8635
Hauptverfasser:	Gherzi, R, Sesti, G, Andraghetti, G, De Pirro, R, Lauro, R, Adezati, L, Cordera, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, immunoglobulins Antibodies, Monoclonal Antigen-Antibody Complex - analysis beta -subunits Biological and medical sciences Carcinoma, Hepatocellular - metabolism Cell Line Fundamental and applied biological sciences. Psychology Fundamental immunology Homeostasis Humans insulin Kinetics Liver Neoplasms - metabolism Liver Neoplasms, Experimental - metabolism Macromolecular Substances Molecular immunology Monoclonal antibodies protein-tyrosine kinase Protein-Tyrosine Kinases - metabolism Rats Receptor, Insulin - immunology Receptor, Insulin - metabolism
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