Causes of Death and Recurrence after Surgery for Early Gastric Cancer
The postoperative course of 172 patients with early gastric cancer (EGC) was followed for a median 7 years to evaluate the causes of death, incidence and patterns of recurrence, and characteristic findings in the recurrent cases. The cumulative 10‐year mortality rate (± SE) was 22 ± 3.7%. Seven pati...
Gespeichert in:
| Veröffentlicht in: | World journal of surgery 1997-05, Vol.21 (4), p.434-439 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 439 |
|---|---|
| container_issue | 4 |
| container_start_page | 434 |
| container_title | World journal of surgery |
| container_volume | 21 |
| creator | Guadagni, Stefano Catarci, Marco Kinoshitá, Taira Valenti, Marco De Bernardinis, Giancarlo Carboni, Manlio |
| description | The postoperative course of 172 patients with early gastric cancer (EGC) was followed for a median 7 years to evaluate the causes of death, incidence and patterns of recurrence, and characteristic findings in the recurrent cases. The cumulative 10‐year mortality rate (± SE) was 22 ± 3.7%. Seven patients (4.1%) died of operative mortality, 11 (6.4%) died of a recurrence of the gastric cancer, and 13 (7.6%) died of unrelated causes. Unrelated causes of death were metachronous primary cancer (n = 6), cardiovascular disease (n= 2), pneumonia (n= 3), sepsis (n= 1), and car accident (n= 1). Four patients died from gastric stump recurrence, three from liver metastases, two from lymph node metastases, and two from peritoneal dissemination. Using Cox multivariate analysis, histologic type had the most significant effect on recurrence. Although influenced by the tumor nature, the EGC prognosis is relatively good. Based on the results of this study, particularly in Western institutions, histologic examination of resection margins and lymphadenectomy should be improved. Moreover, patients must be carefully followed for late recurrence and metachronous cancer. |
| doi_str_mv | 10.1007/PL00012266 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78976806</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2693707311</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4636-9b9f4c59908b57fff6d648afec1a2a30df108368161e9388a75443cbd60189e53</originalsourceid><addsrcrecordid>eNp90M9LwzAUB_AgypzTi3chIHgQqknT5sdR6pzKQHGKx5KmL9rRtZq0SP97IxsqHjy9B-_Dl8cXoUNKzigh4vx-Tgihccz5FhrThMVRzGK2jcaE8STslO2iPe-XAQlO-AiNVFCpEGM0zXTvwePW4kvQ3SvWTYkfwPTOQWMAa9uBw4vevYAbsG0dnmpXD3imfecqgzMdlNtHO1bXHg42c4KerqaP2XU0v5vdZBfzyCSc8UgVyiYmVYrIIhXWWl7yRGoLhupYM1JaSiTjknIKikmpRZokzBQlJ1QqSNkEnaxz31z73oPv8lXlDdS1bqDtfS6kElwSHuDxH7hse9eE33JKYioSJVMW1OlaGdd678Dmb65aaTcElH81m_80G_DRJrIvVlB-002V4Z6u7x9VDcM_Sfnz7eJX7idSSH-m</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1021749853</pqid></control><display><type>article</type><title>Causes of Death and Recurrence after Surgery for Early Gastric Cancer</title><source>MEDLINE</source><source>SpringerNature Journals</source><source>Wiley Online Library All Journals</source><creator>Guadagni, Stefano ; Catarci, Marco ; Kinoshitá, Taira ; Valenti, Marco ; De Bernardinis, Giancarlo ; Carboni, Manlio</creator><creatorcontrib>Guadagni, Stefano ; Catarci, Marco ; Kinoshitá, Taira ; Valenti, Marco ; De Bernardinis, Giancarlo ; Carboni, Manlio</creatorcontrib><description>The postoperative course of 172 patients with early gastric cancer (EGC) was followed for a median 7 years to evaluate the causes of death, incidence and patterns of recurrence, and characteristic findings in the recurrent cases. The cumulative 10‐year mortality rate (± SE) was 22 ± 3.7%. Seven patients (4.1%) died of operative mortality, 11 (6.4%) died of a recurrence of the gastric cancer, and 13 (7.6%) died of unrelated causes. Unrelated causes of death were metachronous primary cancer (n = 6), cardiovascular disease (n= 2), pneumonia (n= 3), sepsis (n= 1), and car accident (n= 1). Four patients died from gastric stump recurrence, three from liver metastases, two from lymph node metastases, and two from peritoneal dissemination. Using Cox multivariate analysis, histologic type had the most significant effect on recurrence. Although influenced by the tumor nature, the EGC prognosis is relatively good. Based on the results of this study, particularly in Western institutions, histologic examination of resection margins and lymphadenectomy should be improved. Moreover, patients must be carefully followed for late recurrence and metachronous cancer.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/PL00012266</identifier><identifier>PMID: 9143577</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer‐Verlag</publisher><subject>Aged ; Cause of Death ; Cohort Studies ; Early Gastric Cancer ; Female ; Follow-Up Studies ; Gastrectomy - mortality ; Humans ; Italy - epidemiology ; Liver Metastasis ; Lymph Node Metastasis ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Recurrence, Local - mortality ; Neoplasm Staging ; Pneumonia ; Postoperative Complications - mortality ; Precancerous Conditions - mortality ; Precancerous Conditions - pathology ; Precancerous Conditions - surgery ; Resection Margin ; Stomach Neoplasms - mortality ; Stomach Neoplasms - pathology ; Stomach Neoplasms - surgery ; Survival Analysis</subject><ispartof>World journal of surgery, 1997-05, Vol.21 (4), p.434-439</ispartof><rights>1997 International Society of Surgery</rights><rights>by the Société Internationale de Chirugie 1997</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4636-9b9f4c59908b57fff6d648afec1a2a30df108368161e9388a75443cbd60189e53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1007%2FPL00012266$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1007%2FPL00012266$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9143577$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guadagni, Stefano</creatorcontrib><creatorcontrib>Catarci, Marco</creatorcontrib><creatorcontrib>Kinoshitá, Taira</creatorcontrib><creatorcontrib>Valenti, Marco</creatorcontrib><creatorcontrib>De Bernardinis, Giancarlo</creatorcontrib><creatorcontrib>Carboni, Manlio</creatorcontrib><title>Causes of Death and Recurrence after Surgery for Early Gastric Cancer</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><description>The postoperative course of 172 patients with early gastric cancer (EGC) was followed for a median 7 years to evaluate the causes of death, incidence and patterns of recurrence, and characteristic findings in the recurrent cases. The cumulative 10‐year mortality rate (± SE) was 22 ± 3.7%. Seven patients (4.1%) died of operative mortality, 11 (6.4%) died of a recurrence of the gastric cancer, and 13 (7.6%) died of unrelated causes. Unrelated causes of death were metachronous primary cancer (n = 6), cardiovascular disease (n= 2), pneumonia (n= 3), sepsis (n= 1), and car accident (n= 1). Four patients died from gastric stump recurrence, three from liver metastases, two from lymph node metastases, and two from peritoneal dissemination. Using Cox multivariate analysis, histologic type had the most significant effect on recurrence. Although influenced by the tumor nature, the EGC prognosis is relatively good. Based on the results of this study, particularly in Western institutions, histologic examination of resection margins and lymphadenectomy should be improved. Moreover, patients must be carefully followed for late recurrence and metachronous cancer.</description><subject>Aged</subject><subject>Cause of Death</subject><subject>Cohort Studies</subject><subject>Early Gastric Cancer</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastrectomy - mortality</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Liver Metastasis</subject><subject>Lymph Node Metastasis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Neoplasm Recurrence, Local - mortality</subject><subject>Neoplasm Staging</subject><subject>Pneumonia</subject><subject>Postoperative Complications - mortality</subject><subject>Precancerous Conditions - mortality</subject><subject>Precancerous Conditions - pathology</subject><subject>Precancerous Conditions - surgery</subject><subject>Resection Margin</subject><subject>Stomach Neoplasms - mortality</subject><subject>Stomach Neoplasms - pathology</subject><subject>Stomach Neoplasms - surgery</subject><subject>Survival Analysis</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp90M9LwzAUB_AgypzTi3chIHgQqknT5sdR6pzKQHGKx5KmL9rRtZq0SP97IxsqHjy9B-_Dl8cXoUNKzigh4vx-Tgihccz5FhrThMVRzGK2jcaE8STslO2iPe-XAQlO-AiNVFCpEGM0zXTvwePW4kvQ3SvWTYkfwPTOQWMAa9uBw4vevYAbsG0dnmpXD3imfecqgzMdlNtHO1bXHg42c4KerqaP2XU0v5vdZBfzyCSc8UgVyiYmVYrIIhXWWl7yRGoLhupYM1JaSiTjknIKikmpRZokzBQlJ1QqSNkEnaxz31z73oPv8lXlDdS1bqDtfS6kElwSHuDxH7hse9eE33JKYioSJVMW1OlaGdd678Dmb65aaTcElH81m_80G_DRJrIvVlB-002V4Z6u7x9VDcM_Sfnz7eJX7idSSH-m</recordid><startdate>199705</startdate><enddate>199705</enddate><creator>Guadagni, Stefano</creator><creator>Catarci, Marco</creator><creator>Kinoshitá, Taira</creator><creator>Valenti, Marco</creator><creator>De Bernardinis, Giancarlo</creator><creator>Carboni, Manlio</creator><general>Springer‐Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>199705</creationdate><title>Causes of Death and Recurrence after Surgery for Early Gastric Cancer</title><author>Guadagni, Stefano ; Catarci, Marco ; Kinoshitá, Taira ; Valenti, Marco ; De Bernardinis, Giancarlo ; Carboni, Manlio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4636-9b9f4c59908b57fff6d648afec1a2a30df108368161e9388a75443cbd60189e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Aged</topic><topic>Cause of Death</topic><topic>Cohort Studies</topic><topic>Early Gastric Cancer</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastrectomy - mortality</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Liver Metastasis</topic><topic>Lymph Node Metastasis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Neoplasm Recurrence, Local - mortality</topic><topic>Neoplasm Staging</topic><topic>Pneumonia</topic><topic>Postoperative Complications - mortality</topic><topic>Precancerous Conditions - mortality</topic><topic>Precancerous Conditions - pathology</topic><topic>Precancerous Conditions - surgery</topic><topic>Resection Margin</topic><topic>Stomach Neoplasms - mortality</topic><topic>Stomach Neoplasms - pathology</topic><topic>Stomach Neoplasms - surgery</topic><topic>Survival Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guadagni, Stefano</creatorcontrib><creatorcontrib>Catarci, Marco</creatorcontrib><creatorcontrib>Kinoshitá, Taira</creatorcontrib><creatorcontrib>Valenti, Marco</creatorcontrib><creatorcontrib>De Bernardinis, Giancarlo</creatorcontrib><creatorcontrib>Carboni, Manlio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guadagni, Stefano</au><au>Catarci, Marco</au><au>Kinoshitá, Taira</au><au>Valenti, Marco</au><au>De Bernardinis, Giancarlo</au><au>Carboni, Manlio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Causes of Death and Recurrence after Surgery for Early Gastric Cancer</atitle><jtitle>World journal of surgery</jtitle><addtitle>World J Surg</addtitle><date>1997-05</date><risdate>1997</risdate><volume>21</volume><issue>4</issue><spage>434</spage><epage>439</epage><pages>434-439</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>The postoperative course of 172 patients with early gastric cancer (EGC) was followed for a median 7 years to evaluate the causes of death, incidence and patterns of recurrence, and characteristic findings in the recurrent cases. The cumulative 10‐year mortality rate (± SE) was 22 ± 3.7%. Seven patients (4.1%) died of operative mortality, 11 (6.4%) died of a recurrence of the gastric cancer, and 13 (7.6%) died of unrelated causes. Unrelated causes of death were metachronous primary cancer (n = 6), cardiovascular disease (n= 2), pneumonia (n= 3), sepsis (n= 1), and car accident (n= 1). Four patients died from gastric stump recurrence, three from liver metastases, two from lymph node metastases, and two from peritoneal dissemination. Using Cox multivariate analysis, histologic type had the most significant effect on recurrence. Although influenced by the tumor nature, the EGC prognosis is relatively good. Based on the results of this study, particularly in Western institutions, histologic examination of resection margins and lymphadenectomy should be improved. Moreover, patients must be carefully followed for late recurrence and metachronous cancer.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer‐Verlag</pub><pmid>9143577</pmid><doi>10.1007/PL00012266</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-2313 |
| ispartof | World journal of surgery, 1997-05, Vol.21 (4), p.434-439 |
| issn | 0364-2313 1432-2323 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78976806 |
| source | MEDLINE; SpringerNature Journals; Wiley Online Library All Journals |
| subjects | Aged Cause of Death Cohort Studies Early Gastric Cancer Female Follow-Up Studies Gastrectomy - mortality Humans Italy - epidemiology Liver Metastasis Lymph Node Metastasis Male Middle Aged Multivariate Analysis Neoplasm Recurrence, Local - mortality Neoplasm Staging Pneumonia Postoperative Complications - mortality Precancerous Conditions - mortality Precancerous Conditions - pathology Precancerous Conditions - surgery Resection Margin Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stomach Neoplasms - surgery Survival Analysis |
| title | Causes of Death and Recurrence after Surgery for Early Gastric Cancer |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T18%3A12%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Causes%20of%20Death%20and%20Recurrence%20after%20Surgery%20for%20Early%20Gastric%20Cancer&rft.jtitle=World%20journal%20of%20surgery&rft.au=Guadagni,%20Stefano&rft.date=1997-05&rft.volume=21&rft.issue=4&rft.spage=434&rft.epage=439&rft.pages=434-439&rft.issn=0364-2313&rft.eissn=1432-2323&rft_id=info:doi/10.1007/PL00012266&rft_dat=%3Cproquest_cross%3E2693707311%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1021749853&rft_id=info:pmid/9143577&rfr_iscdi=true |