Hypertonic Saline Resuscitation Decreases Susceptibility to Sepsis after Hemorrhagic Shock

BACKGROUND We hypothesized that improvements in cellular immune function after hypertonic saline (HTS) resuscitation will alter the outcome of sepsis after hemorrhage. METHODS To test this hypothesis, a two-hit model was used. Hemorrhage was induced in BALB/c mice by catheterizing the femoral artery...

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Veröffentlicht in:	The Journal of Trauma: Injury, Infection, and Critical Care Infection, and Critical Care, 1997-04, Vol.42 (4), p.602-607
Hauptverfasser:	Coimbra, Raul, Hoyt, David B., Junger, Wolfgang G., Angle, Niren, Wolf, Paul, Loomis, William, Evers, Michael F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Disease Susceptibility Drug Evaluation, Preclinical Immunity, Cellular Male Mice Mice, Inbred BALB C Random Allocation Resuscitation - methods Saline Solution, Hypertonic - therapeutic use Sepsis - etiology Shock, Hemorrhagic - complications Shock, Hemorrhagic - immunology Shock, Hemorrhagic - therapy Survival Analysis
Online-Zugang:	Volltext
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