Effects of Thiazolidinediones on Growth and Differentiation of Human Aorta and Coronary Myocytes

Thiazolidinediones, insulin-sensitizing agents that lower insulin and lipid levels in insulin-resistant states, block agonist-induced Ca 2+ entry into vascular smooth muscle (VSM) cells in vitro and lower blood pressure in animals and humans in vivo. In this study, we investigated the effects of cig...

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Veröffentlicht in:	American journal of hypertension 1997-04, Vol.10 (4), p.440-446
Hauptverfasser:	Morikang, Ebenezer, Benson, Stephen C., Kurtz, Theodore W., Pershadsingh, Harrihar A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta - pathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cell Division - drug effects Cells, Cultured Chromans - pharmacology coronary artery Coronary Vessels - pathology differentiation DNA synthesis growth factor human Humans Hypoglycemic Agents - pharmacology Medical sciences Muscle, Smooth, Vascular - pathology platelet-derived growth factor proliferation Thiazoles - pharmacology Thiazolidinedione Thiazolidinediones vascular smooth muscle
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