Synovial sarcoma: immunohistochemical expression of p-glycoprotein and glutathione s-transferase-pi and clinical drug resistance

Our purpose was to study the role of the expression of P-glycoprotein (Pgp) and glutatione S transferase-pi (GST pi) in predicting the response to chemotherapy, relapse-free interval, and survival of patients with synovial sarcoma (SS). Thirty-seven cases of primary SS, without regional lymph node o...

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Veröffentlicht in:	Pathology, research and practice research and practice, 1997, Vol.193 (1), p.21-36
Hauptverfasser:	Lopes, José M., Bruland, Øyvind S., Bjerkehagen, Bodil, Carolina Silva, M., Holm, Ruth, Pettersen, Erik O., Solheim, Øyvin P., Sobrinho-Simões, Manuel, Nesland, Jahn M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over ATP-Binding Cassette, Sub-Family B, Member 1 - biosynthesis Biomarkers, Tumor - biosynthesis Child DNA, Neoplasm - analysis Drug resistance Drug Resistance, Neoplasm Female Flow Cytometry Glutathione S transferase-pi Glutathione Transferase - biosynthesis Humans Immunohistochemistry Isoenzymes - biosynthesis Joint Diseases - drug therapy Joint Diseases - metabolism Joint Diseases - pathology Male Middle Aged P glycoprotein Retrospective Studies Sarcoma, Synovial - drug therapy Sarcoma, Synovial - metabolism Sarcoma, Synovial - pathology Soft Tissue Neoplasms - drug therapy Soft Tissue Neoplasms - metabolism Soft Tissue Neoplasms - pathology Survival Rate Synovial sarcoma
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