Phenotypic differences in dextromethorphan metabolism

Polymorphic differences in dextromethorphan metabolism were observed in three studies conducted in a total of 44 subjects (of Dutch origin) administered 60 mg dextromethorphan hydrobromide as an OROS tablet. Mean plasma dextromethorphan (DM) concentrations after a single dose and at steady state wer...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pharmaceutical research 1989, Vol.6 (1), p.13-19
Hauptverfasser:	VETTICADEN, S. J, CABANA, B. E, PRASAD, V. K, PURICH, E. D, JONKMAN, J. H. J, DE ZEEUW, R, BALL, L, LEESON, L. J, BRAUN, R. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Biological and medical sciences Dextromethorphan - analogs & derivatives Dextromethorphan - blood Dextromethorphan - metabolism Dextromethorphan - pharmacokinetics Dextrorphan - blood General pharmacology Humans Levorphanol - analogs & derivatives Medical sciences Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Phenotype
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!