Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

Rho family proteins are known to regulate actin organization in fibroblasts, but their functions in cells of haematopoietic origin have not been studied in detail. Bac1.2F5 cells are a colony-stimulating factor-1 (CSF-1)-dependent murine macrophage cell line; CSF-1 stimulates their proliferation and...

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Veröffentlicht in:	Journal of cell science 1997-03, Vol.110 ( Pt 6) (6), p.707-720
Hauptverfasser:	Allen, W E, Jones, G E, Pollard, J W, Ridley, A J
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals cdc42 GTP-Binding Protein Cell Adhesion Cell Cycle Proteins - metabolism Cell Line GTP-Binding Proteins - metabolism Integrin beta1 - metabolism Macrophage Colony-Stimulating Factor - pharmacology Macrophages - cytology Macrophages - drug effects Macrophages - metabolism Mice rac GTP-Binding Proteins
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