Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures

BACKGROUND Polyunsaturated fatty acids (n‐6) are reported to selectively kill malignant cells. Most investigations, however, did not compare neoplastic with non‐neoplastic cells from the same tissue type. Here we evaluate the effects of n‐6 fatty acids on a non‐neoplastic epithelium cell line (CAPE)...

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Veröffentlicht in:	The Prostate 1997-04, Vol.31 (1), p.29-36
Hauptverfasser:	Griffiths, Gareth, Jones, Helen E., Eaton, Colby L., Stobart, A. Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Arachidonic Acid - metabolism Arachidonic Acid - pharmacology Biological and medical sciences canine prostatic adenocarcinoma Cell Division - drug effects Cells, Cultured - drug effects Dogs Experimental renal and urinary tract tumors gamma-Linolenic Acid - metabolism gamma-Linolenic Acid - pharmacology Linoleic Acid Linoleic Acids - metabolism Linoleic Acids - pharmacology Lipids - analysis Male Medical sciences n-6 fatty acids Prostate - chemistry Prostate - metabolism Prostate - pathology Prostatic Neoplasms - chemistry Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Tumor Cells, Cultured - drug effects Tumors γ-linolenic acid cytotoxicity
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