Randomized trial using piperacillin versus ampicillin and amikacin for treatment of premature neonates with risk factors for sepsis

Premature infants with risk factors for early onset sepsis who were less than seven days of age were blindly randomized to receive either piperacillin and placebo (200 infants) or ampicillin and amikacin (196 infants). One of 30 treated infants developed positive blood cultures. The overall mortalit...

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Veröffentlicht in:	European journal of clinical microbiology & infectious diseases 1989-03, Vol.8 (3), p.241-244
Hauptverfasser:	Hammerberg, O, Kurnitzki, C, Watts, J, Rosenbloom, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amikacin - therapeutic use Ampicillin - therapeutic use Bacterial Infections - drug therapy Drug Therapy, Combination - therapeutic use Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans Infant, Newborn Infant, Premature, Diseases - drug therapy Piperacillin - therapeutic use Random Allocation Risk Factors Sepsis - drug therapy
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